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Merck
CN

191906

羟丙基纤维素

average Mw ~1,000,000, powder, 20 mesh particle size (99% through)

别名:

Cellulose & cellulose derivatives

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关于此项目

化学文摘社编号:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
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description

biological oxygen demand (BOD) 14,000 ppm

Quality Level

form

powder

autoignition temp.

752 °F

mol wt

average Mw ~1,000,000

impurities

<5 wt. %

particle size

20 mesh (99% through)

pH

5.0-8.5

interfacial tension mineral oil

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

viscosity

1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)

solubility

H2O: insoluble (above 45 °C), polar organic solvents: soluble

density

0.5 g/mL at 25 °C (lit.)

SMILES string

N(C)(C)c1cc(c(cc1)C(N)CC)C

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI key

RRHXDYJWVYFMKV-UHFFFAOYSA-N

Application

  • 热响应性水性泡沫:研究人员已经研究了羟丙基纤维素作为绿色聚合物的性质,它可以随温度变化改变溶解性,适用于响应性泡沫应用 (Braunschweig, 2019)。
  • 水溶液中的相互作用机制:一项有关溶液中羟丙基纤维素和水相互作用的研究,重点关注了聚合物链长在确定溶液物理性质中的重要性 (Martin-Pastor and Stoyanov, 2020)。
  • 腐蚀抑制:研究显示了羟丙基纤维素作为酸性环境中铝腐蚀抑制剂的有效性,重点介绍了其在材料科学和工程应用中的潜力 (Jarkas et al., 2019)。
  • 口腔崩解膜:该应用涉及羟丙基纤维素膜的配方设计,目的在于改善药物的递送和溶出曲线,它在药物递送和药物科学中有重要意义 (Takeuchi et al., 2018)。


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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Satomi Onoue et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 492-499 (2012-04-14)
The present study was undertaken to develop a solid self-emulsifying drug delivery system of coenzyme Q(10) (CoQ(10)/s-SEDDS) with high photostability and oral bioavailability. The CoQ(10)/s-SEDDS was prepared by spray-drying an emulsion preconcentrate containing CoQ(10), medium-chain triglyceride, sucrose ester of fatty
Alexandre Monteiro et al.
Drug development and industrial pharmacy, 39(2), 266-283 (2012-04-17)
Nanoparticles of BCS Class II drugs are produced in wet stirred media mills operating in batch or recirculation mode with the goal of resolving the poor water-solubility issue. Scant information is available regarding the continuous production of drug nanoparticles via
In-Hwan Beak et al.
Chemical & pharmaceutical bulletin, 60(11), 1468-1473 (2012-11-06)
In this study, amorphous solid dispersions containing dutasteride and various excipients, manufactured by spray-drying processes, were characterized to determine the effects on their ability to form supersaturated solutions and to identify the effects of supersaturation on increasing the bioavailability of



全球贸易项目编号

货号GTIN
411124-50ML04061838127297
406139-25ML04061838127259
411124-100ML04061838127280
191906-5G04061833320440
191906-100G04061838760388
191906-250G04061833595268