Quality Level
assay
95%
form
crystals
bp
75-76 °C/10 mmHg (lit.)
mp
63-66 °C (lit.)
functional group
chloro
SMILES string
Clc1ncccn1
InChI
1S/C4H3ClN2/c5-4-6-2-1-3-7-4/h1-3H
InChI key
UNCQVRBWJWWJBF-UHFFFAOYSA-N
General description
2-氯嘧啶可与芳基卤化物发生经钴催化的交叉偶联反应。
Application
2-氯嘧啶可用于合成:
- 新 双(2-(嘧啶-2-基)乙氧基)烷烃
- 4′-(1,1′-(5-(2-甲氧基苯氧基)-[2,2′-联嘧啶基]-4,6-二基)双(1H-吡唑-3,1-二基))二苯胺荧光染料,可用作蛋白质测定的生物传感器
- 顺式-和 反式-氢化吡咯并[2,3]吡啶衍生物
- 2-氨基-4-杂芳基嘧啶
Other Notes
残留物为 2-羟基嘧啶
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
208.4 °F - closed cup
flash_point_c
98 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Vangavaragu Jhansi Rani et al.
Archiv der Pharmazie, 345(8), 663-669 (2012-05-18)
The pyrimidine nucleus is an important component of nucleic acids (DNA and RNA) and vitamins (B(2) and folic acid). It is evident from the literature that pyrimidine derivatives possess a wide spectrum of biological activities such as antioxidant, anticancer, antibacterial
Matthew G Bursavich et al.
Organic letters, 7(19), 4113-4116 (2005-09-09)
[reaction: see text] An expedient synthesis of diverse 2-amino-4-heteroarylpyrimidines via a 2-chloropyrimidine intermediate is described. A series of potentially biologically active analogues have been synthesized in two parallel steps to afford focused arrays.
Igor Goljer et al.
Chirality, 21(7), 681-691 (2008-09-17)
Reaction of (S)- or (R)-3-aminoquinuclidine with 2-chloropyrimidine or 2-bromopyrimidine led to an unexpected formation of both cis- and trans-octahydropyrrolo [2,3]pyridine derivatives. A single-step synthesis of two of the four stereoisomers of these octahydropyrrolo[2,3]pyridine derivatives provides a convenient way of generating
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 193291-10G | 04061838760746 |
| 193291-50G | 04061832241999 |
