219096
D -天冬氨酸
99%, for peptide synthesis, ReagentPlus®
别名:
(R)-(-)-氨基琥珀酸, (R)-2-氨基琥珀酸
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关于此项目
线性分子式:
HO2CCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
133.10
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
217-234-6
MDL number:
Beilstein/REAXYS Number:
1723529
产品名称
D -天冬氨酸, ReagentPlus®, 99%
Quality Level
product line
ReagentPlus®
assay
99%
form
powder
optical activity
[α]20/D −24°, c = 2.3 in 6 M HCl
optical purity
ee: 98% (GLC)
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
application(s)
peptide synthesis
SMILES string
N[C@H](CC(O)=O)C(O)=O
InChI
1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
InChI key
CKLJMWTZIZZHCS-UWTATZPHSA-N
Gene Information
rat ... Slc1a3(29483)
Application
- 代谢组学分析鉴定差异代谢物作为急性心肌梗死的生物标志物：这项研究利用代谢组学来鉴定急性心肌梗死的生物标志物，展示了D-天冬氨酸在氨基酸代谢中的作用及其潜在的诊断应用。（Zhou等人，2024年）。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Noriko Fujii et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3141-3147 (2011-07-05)
Homochirality is essential for life. L-Amino acids are exclusively used as substrates for the polymerization and formation of peptides and proteins in living systems. However, d-amino acids, which are enantiomers of L-amino acids, were recently detected in various living organisms
Yuhei Mori et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(29), 3303-3309 (2011-06-04)
UV-B irradiation is one of the risk factors in age-related diseases. We have reported that biologically uncommon D-β-Asp residues accumulate in proteins from sun-exposed elderly human skin. A previous study also reported that carboxymethyl lysine (CML; one of the advanced
Yuanqi Tao et al.
Analytical chemistry, 84(15), 6814-6820 (2012-07-21)
The presence of a single D-amino acid in a peptide is very difficult to detect. Mass spectrometry-based approaches rely on differences in fragmentation between all L-amino acid-containing peptides and single D-amino acid-containing peptides (which are epimers) for identification. The success
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 219096-100G | 04061833540534 |
| 219096-25G | 04061838775818 |