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Merck
CN

234907

2-(二甲氨基)甲基丙烯酸乙酯

contains 700-1000 ppm monomethyl ether hydroquinone as inhibitor, 98%

别名:

甲基丙烯酸二甲氨乙酯

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关于此项目

线性分子式:
CH2=C(CH3)COOCH2CH2N(CH3)2
化学文摘社编号:
分子量:
157.21
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1757048
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vapor density

5.4 (vs air)

Quality Level

vapor pressure

<1 mmHg ( 25 °C)

assay

98%

form

liquid

contains

700-1000 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.439 (lit.)

bp

182-192 °C (lit.)

density

0.933 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CN(C)CCOC(=O)C(C)=C

InChI

1S/C8H15NO2/c1-7(2)8(10)11-6-5-9(3)4/h1,5-6H2,2-4H3

InChI key

JKNCOURZONDCGV-UHFFFAOYSA-N

General description

甲基丙烯酸 2-(二甲氨基)乙酯 (DMAEMA) 是一种甲基丙烯酸衍生物,其可用作生产具有广泛应用的聚合物的单体。DMAEMA最常见的用途是生产阳离子聚合物,这种聚合物具有高电荷,可用于絮凝剂、混凝剂、分散剂和稳定剂等。此外,基于DMAEMA的聚合物由于其优异的生物相容性和生物降解性,已在药物递送系统、组织工程和基因治疗中得到应用。DMAEMA还可用作涂料、粘合剂和纺织品中的改性剂,以改善粘合性、硬度和耐水性等性能。

Application

2-(二甲胺基)甲基丙烯酸乙酯(DMAEMA)可作为起始原料用于合成聚(DMAEMA)和疏水性嵌段共聚物。聚(DMAEMA)是一种对热和pH敏感的生物相容性聚合物,广泛应用于以下应用。

  • 季铵化聚(DMAEMA)可用于制备高效的抗菌磁性颗粒。通过表面引发的ATRP生成的季铵基团的高密度导致了高抗菌活性。
  • 在聚(DMAEMA)刷层(brush layer)中固定的银纳米颗粒可用作表面增强拉曼光谱(SERS)检测有机分子的传感器平台。
  • 它也可用于制备稳定的聚合物基基因传递系统。


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pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

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Ying Wang et al.
Biomacromolecules, 13(8), 2585-2593 (2012-07-05)
Photo- and pH-responsive amphiphilic hyperbranched star copolymers, poly(6-O-methacryloyl-1,2;3,4-di-O-isopropylidene-d-galactopyranose)[poly(2-(N,N-dimethylaminoethyl) methacrylate)-co-poly(1'-(2-methacryloxyethyl)-3',3'-dimethyl-6-nitro-spiro(2H-1-benzo-pyran-2,2'-indoline))](n)s [HPMAlpGP(PDMAEMA-co-PSPMA)(n)], were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization of the DMAEMA and the SPMA using hyperbranched PMAlpGP as a macro RAFT agent. In aqueous solution, the copolymers self-assembled to
Synthesis of well-defined amphiphilic block copolymers with 2-(dimethylamino) ethyl methacrylate by controlled radical polymerization
Zhang Y and Matyjaszewski K
Macromolecules, 32(6), 1763-1766 (1999)
Hong Y Cho et al.
Biomacromolecules, 12(10), 3478-3486 (2011-09-08)
Star polymers with poly(ethylene glycol) (PEG) arms and a degradable cationic core were synthesized by the atom transfer radical copolymerization (ATRP) of poly(ethylene glycol) methyl ether methacrylate macromonomer (PEGMA), 2-(dimethylamino)ethyl methacrylate (DMAEMA), and a disulfide dimethacrylate (cross-linker, SS) via an



全球贸易项目编号

货号GTIN
234907-1L04061838784780
234907-100ML04061837399466