235199
7-甲氧基香豆素-4-乙酸
97%
别名:
7-甲氧基-2-氧代-2H-1-苯并吡喃-4-乙酸
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关于此项目
经验公式（希尔记法）:
C12H10O5
化学文摘社编号:
分子量:
234.20
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
Quality Level
assay
97%
mp
193 °C (dec.) (lit.)
solubility
DMF: soluble 50 mg/mL, clear, colorless to yellow
functional group
carboxylic acid, ester
SMILES string
COc1ccc2C(CC(O)=O)=CC(=O)Oc2c1
InChI
1S/C12H10O5/c1-16-8-2-3-9-7(4-11(13)14)5-12(15)17-10(9)6-8/h2-3,5-6H,4H2,1H3,(H,13,14)
InChI key
ZEKAXIFHLIITGV-UHFFFAOYSA-N
Application
已使用7-甲氧基香豆素-4-乙酸：
- 作为荧光探针，制备两个新型LysB29选择性标记的人胰岛素荧光衍生物
- 在细胞穿膜肽转运蛋白10（tp10）的制备中
- 作为肽的荧光标记
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Alice Ciencialová et al.
Journal of peptide science : an official publication of the European Peptide Society, 10(7), 470-478 (2004-08-10)
The preparation and characterization of two novel LysB29 selectively labelled fluorescent derivatives of human insulin are described. Two probes were chosen: 4-chloro-7-nitrobenz-2-oxa-1,3-diazole (NBD) and 7-methoxycoumarin-4-acetic acid (MCA), which have a relatively small, compact structure and are able to react with
Tianshu Xiao et al.
Nature structural & molecular biology, 28(2), 202-209 (2021-01-13)
Effective intervention strategies are urgently needed to control the COVID-19 pandemic. Human angiotensin-converting enzyme 2 (ACE2) is a membrane-bound carboxypeptidase that forms a dimer and serves as the cellular receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ACE2 is
Stereospecific synthesis ofl-2-amino-3-(7-methoxy-4-coumaryl) propionic acid, an alternative to tryptophan in quenched fluorescent substrates for peptidases.
Knight CG.
Lett. Pept. Sci., 5(1), 1-4 (1998)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 235199-500MG | 04061838784964 |
| 235199-1G | 04061826661826 |