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Merck
CN

261556

(L)-脱氢抗坏血酸

别名:

L-苏-脱氢抗坏血酸

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关于此项目

经验公式(希尔记法):
C6H6O6
化学文摘社编号:
分子量:
174.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352205
EC Number:
207-720-6
MDL number:
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form

powder

mp

228 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

OC[C@H](O)[C@H]1OC(=O)C(=O)C1=O

InChI

1S/C6H6O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-8H,1H2/t2-,5+/m0/s1

InChI key

SBJKKFFYIZUCET-JLAZNSOCSA-N

General description

(L)-脱氢抗坏血酸(DHA)是一种强效糖化剂,由抗坏血酸(维生素)氧化制得。体外研究表明,对于晶状体蛋白糖化反应,DHA的活性远超葡萄糖和果糖。因此,DHA是晚期糖化终产物(AGE)体内形成的关键前体。
DHA的固体为二聚体形式,在溶液中又呈单体形式。

Application

(L)-脱氢抗坏血酸可作为起始原料用于:
  • 与2-甲羟基吲哚反应合成吡喃并[3,4-b]吲哚衍生物。
  • 与间苯三酚通过立体选择性C-C键形成反应合成(−)-抗坏血酸间苯三酚。



存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Simultaneous analysis of ascorbic acid and dehydroascorbic acid in various food samples by High Performance Thin Layer Chromatography (HPTLC).


Jens Lykkesfeldt
Nutrition research (New York, N.Y.), 32(1), 66-69 (2012-01-21)
Ascorbate and dehydroascorbic acid are frequently used as biomarkers of oxidative stress, but their lack of stability ex vivo and rapid postsampling interconversion continue to result in erroneous reference values. One problem is the large variety of vacutainer devices used
Els Vossen et al.
Meat science, 91(1), 29-35 (2012-01-10)
The effect of sodium ascorbate (SA; 500, 750, 1000 mg/kg) and sodium nitrite (SN; 40, 80, 120 mg/kg) doses on the shelf-life stability of liver pâtés was investigated in a full factorial design. Clear dose-dependent responses of the added SN
Oliver Reihl et al.
Carbohydrate research, 339(3), 483-491 (2004-03-12)
Covalently cross-linked proteins are among the major modifications caused by the advanced Maillard reaction. So far, the chemical nature of these aggregates is largely unknown. L-dehydroascorbic acid (DHA, 5), the oxidation product of L-ascorbic acid (vitamin C), is known as



全球贸易项目编号

货号GTIN
261556-1G04061826107522
261556-250MG04061826107546
261556-5G04061826107560