288144
三羰基二氯代钌二聚物
别名:
CORM-2
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关于此项目
线性分子式:
[Ru(CO)3Cl2]2
化学文摘社编号:
分子量:
512.01
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
MDL number:
Quality Level
reaction suitability
core: ruthenium, reagent type: catalyst
SMILES string
[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].Cl[Ru]Cl.Cl[Ru]Cl
InChI
1S/6CO.4ClH.2Ru/c6*1-2;;;;;;/h;;;;;;4*1H;;/q;;;;;;;;;;2*+2/p-4
InChI key
JYHHJVKGDCZCCL-UHFFFAOYSA-J
Application
三羰基二氯钌(II)二聚体可用于氘化反应以标记仲胺。还可与环戊二烯并[l]菲基和c环戊二烯[a]苊基配体反应合成外消旋催化剂。
用于药理学研究的一氧化碳释放分子包括：
用作活性氧介导的细菌杀灭的一氧化碳供体
- 凝血增强和纤溶脆弱性减弱
- P2X4作为可能靶点的研究
- 血栓生长或崩解的可能改变
- 增强纤维蛋白原作为凝血酶底物的作用
- 气体传输器对离子传输的调节
用作活性氧介导的细菌杀灭的一氧化碳供体
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
V G Nielsen et al.
Human & experimental toxicology, 36(7), 727-733 (2016-08-05)
Hypofibrinogenemia is an important clinical consequence following envenomation by Lachesis muta muta, usually attenuated or prevented by administration of antivenom. The venom of L. m. muta contains both a metalloproteinase fibrinogenase and a serine protease thrombin-like enzyme, and exposure of
Po-Min Yang et al.
Vascular pharmacology, 87, 209-218 (2016-10-11)
The production of nitric oxide (NO) by endothelial NO synthase (eNOS) plays a major role in maintaining vascular homeostasis. This study elucidated the potential role of carbon monoxide (CO)-releasing molecules (CORMs) in NO production and explored the underlying mechanisms in
Vance G Nielsen et al.
Basic & clinical pharmacology & toxicology, 120(2), 207-212 (2016-08-23)
Since the introduction of antivenom administration over a century ago to treat venomous snake bite, it has been the most effective therapy for saving life and limb. However, this treatment is not always effective and not without potential life-threatening side
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 288144-500MG | 04061826273418 |