assay
98%
form
powder
mp
250-253 °C (lit.)
SMILES string
[Na+].CCCC([O-])=O
InChI
1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChI key
MFBOGIVSZKQAPD-UHFFFAOYSA-M
Gene Information
mouse ... ENSMUSG00000061062(15181)
General description
丁酸钠是丁酸的钠盐形式。它是一种已知抑制肿瘤细胞生长的天然化合物，并研究了其在人乳腺癌细胞系（MCF7）中的生物活性。丁酸钠可能是治疗人脊髓性肌萎缩症患者的有效药物。
丁酸钠是一种脂肪酸钠盐，可用作酚的酰化剂。
丁酸钠是一种脂肪酸钠盐，可用作酚的酰化剂。
Application
丁酸钠可作为反应剂，使用9-硼双环 [3.3.1] 壬烷（9-BBN）在 THF 中通过还原反应制备正丁醛。此外，还可通过还原氧化反应转化成丁醛硼烷和氯铬酸吡啶。采用基于离子液的氯亚胺试剂，丁酸钠通过光延反应与不同的醇发生反应生成酯。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Exceptionally facile conversion of carboxylic acid salts to aldehydes by reductive oxidation with borane and pyridinium chlorochromate
Cha JS, et al.
Bull. Korean Chem. Soc., 22(3), 325-326 (2001)
J G Chang et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(17), 9808-9813 (2001-08-16)
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of the anterior horn cells of the spinal cord, leading to muscular paralysis with muscular atrophy. No effective treatment of this disorder is presently available. Studies of the
D Coradini et al.
International journal of cancer, 81(3), 411-416 (1999-04-21)
The potential clinical utility of sodium butyrate, a natural compound known to inhibit tumor-cell growth, is hampered by the difficulty of achieving effective in-vivo concentrations. The short half-life (about 5 minutes) of sodium butyrate results in rapid metabolism and excretion.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 303410-500G | 04061826666371 |
| 303410-100G | 04061826666364 |
| 303410-5G | 04061826666388 |