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363057

6-O-甲基鸟嘌呤

97%

别名:

2-氨基-6-甲氧基嘌呤, 6-甲氧基鸟嘌呤

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关于此项目

经验公式（希尔记法）:
C6H7N5O
化学文摘社编号:
20535-83-5
分子量:
165.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24862349
MDL number:
MFCD00133009
Beilstein/REAXYS Number:
645384
Assay:
97%
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Quality Level

200

assay

97%

mp

>300 °C (lit.)

SMILES string

COc1nc(N)nc2[nH]cnc12

InChI

1S/C6H7N5O/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11)

InChI key

BXJHWYVXLGLDMZ-UHFFFAOYSA-N

Gene Information

human ... CDK2(1017), MGMT(4255)

General description

6-O-甲基鸟嘌呤是一种嘌呤衍生物，它的结合亲和力已通过使用等温滴定热法（ITC）利用枯草芽孢杆菌xpt-pbuX鸟嘌呤核糖开关（GR）进行了检查。6-O-甲基鸟嘌呤是在一系列纯化的tRNA制剂的烷基化过程中通过与致癌物N-甲基-N-亚硝基脲反应而形成的。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKBV4540V
MKBB2035
05417JH
16217JN
13708TW

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A E Pegg
Chemico-biological interactions, 6(6), 393-406 (1973-06-01)
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Cultured human cells are invaluable biological models for mechanistic studies of genotoxic chemicals and drugs. Continuing replacement of animals in toxicity testing will further increase the importance of in vitro cell systems, which should accurately reproduce key in vivo characteristics
Vitaly F Latypov et al.
Molecular cell, 47(1), 50-60 (2012-06-05)
Nucleotide excision repair (NER) has long been known to remove DNA lesions induced by chemical carcinogens, and the molecular mechanism has been partially elucidated. Here we demonstrate that in Schizosaccharomyces pombe a DNA recognition protein, alkyltransferase-like 1 (Atl1), can play
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全球贸易项目编号

货号GTIN
363057-500MG04061833472989