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379409

1,2-二甲基-3-羟基-4-吡啶酮

Name: 1,2-二甲基-3-羟基-4-吡啶酮
Brand: ALDRICH

98%

别名:

去铁酮

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关于此项目

经验公式（希尔记法）:

C₇H₉NO₂

化学文摘社编号:

30652-11-0

分子量:

139.15

NACRES:

NA.22

PubChem Substance ID:

24863630

UNSPSC Code:

12352100

MDL number:

MFCD00134497

Assay:

98%

Form:

powder

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属性

Quality Level

100

assay

98%

form

powder

mp

272-275 °C (lit.)

functional group

ketone

SMILES string

CN1C=CC(=O)C(O)=C1C

InChI

1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3

InChI key

TZXKOCQBRNJULO-UHFFFAOYSA-N

说明

General description

3-羟基-1,2-二甲基-4(1H)-吡啶酮（Hdpp，去铁酮）是一种羟基酮衍生物。它在酸性水溶液中与铀酰盐[UO₂(NO₃)₂]反应，得到单核复合物（[UO₂(dpp)(Hdpp)₂(H₂O)]ClO₄）。已通过X射线研究分析了这些复合物的结构和几何结构。

Application

3-羟基-1,2-二甲基-4(1H)-吡啶酮（OH-吡啶酮）可用于杀菌试验。它已被用作羟基酮螯合剂，并且已经评估了其对人口腔正常和肿瘤细胞的细胞毒作用。

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines.

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Anticancer research, 24(2B), 755-762 (2004-05-27)

Hydroxyketone chelators, deferiprone (HK1), maltol (HK3) and their related compounds (HK2, 4-8), were characterized for their cytotoxic profiles against oral human normal and tumor cells. Most hydroxyketones except HK6 showed relatively higher tumor-specific cytotoxicity. Deferiprone (HK1), which showed the highest

Synthesis, structure, and solution dynamics of UO22+-hydroxy ketone compounds [UO2(ma)2(H2O)] and [UO2(dpp)(Hdpp)2(H2O)]ClO4 [ma = 3-hydroxy-2-methyl-4-pyrone, Hdpp = 3-hydroxy-1,2-dimethyl-4(1H)-pyridone].

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Inorganic chemistry, 43(26), 8336-8345 (2004-12-21)

Reaction of [UO(2)(NO(3))(2)] with the hydroxy ketones 3-hydroxy-2-methyl-4-pyrone (Hma) and 3-hydroxy-1,2-dimethyl-4(1H)-pyridone (Hdpp) in aqueous acidic solutions (pH approximately 3) yields the compounds [UO(2)(ma)(2)(H(2)O)].H(2)O (1.H(2)O) and [UO(2)(dpp)(Hdpp)(2)(H(2)O)]ClO(4) (2), respectively. X-ray diffraction shows that the geometry around the metal ion in both

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379409-25G	04061831837070
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