41996
N-羟基-7-偶氮苯并三氮唑 溶液
~0.6 M in DMF, for peptide synthesis
别名:
3H-[1,2,3]-三唑[4,5-b]吡啶-3-醇, HOAt
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关于此项目
经验公式（希尔记法）:
C5H4N4O
化学文摘社编号:
分子量:
136.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Beilstein/REAXYS Number:
1211115
产品名称
N-羟基-7-偶氮苯并三氮唑 溶液, ~0.6 M in DMF
form
liquid
Quality Level
reaction suitability
reaction type: Addition Reactions
concentration
~0.6 M in DMF
impurities
<1.0% water
refractive index
n20/D 1.441
density
0.978 g/mL at 20 °C
application(s)
peptide synthesis
SMILES string
On1nnc2cccnc12
InChI
1S/C5H4N4O/c10-9-5-4(7-8-9)2-1-3-6-5/h1-3,10H
InChI key
FPIRBHDGWMWJEP-UHFFFAOYSA-N
General description
1-羟基-7-氮杂苯并三唑溶液，又称3H-[1,2,3]-三唑并[4,5-b]吡啶-3-醇，是一种苯并三唑类添加剂，常用作氨基酸和肽的偶联试剂。它还被用于最小化对映异构体生成。
Application
1-羟基-7-氮杂苯并三唑溶液被用作手性肽核酸的固相合成试剂。
Other Notes
偶联添加剂，用于肽合成中的高效无外消旋偶联； 片段偶联。
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
存储类别
3 - Flammable liquids
flash_point_f
136.4 °F - closed cup
flash_point_c
58 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
L.A. Carpino, A. El-Faham
Tetrahedron, 55, 6813-6813 (1999)
Hsuan-Ni Lin et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 34(11), 1883-1893 (2016-02-27)
Fracture healing is regulated by a variety of inflammatory mediators and growth factors which act over time to regenerate the injured tissue. This study used a mouse femur fracture model to quantify the temporal expression pattern of lipid mediators, cytokines
Y. Nishiyama et al.
Tetrahedron Letters, 42, 8789-8789 (2001)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 41996-25ML-F | 04061838119759 |
| 41996-100ML-F | 04061838119742 |