Quality Level
assay
98%
form
solid
mp
256-271 °C (lit.)
functional group
ketone, phenyl
SMILES string
Oc1cc2OC(=CC(=O)c2c(O)c1O)c3ccccc3
InChI
1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChI key
FXNFHKRTJBSTCS-UHFFFAOYSA-N
Gene Information
mouse ... Hexa(15211)
rat ... Alox15(81639), Alox5(25290)
General description
黄芩素是黄酮类化合物，是黄嘌呤氧化酶抑制剂。研究了黄芩素在人外周白细胞中的抗炎作用。
Application
黄芩素曾用于研究脂氧合酶的体外定量抑制。
Biochem/physiol Actions
尼泊尔和中日天然药中的黄酮类成分。 黄芩素是黄芩的主要黄酮，可抑制花生四烯酸代谢的12-脂氧合酶（12-LOX）途径，该途径可抑制癌细胞增殖并诱导细胞凋亡。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
商品
抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
相关内容
Nina M Høyland-Kroghsbo et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(1), 131-135 (2016-11-17)
CRISPR-Cas are prokaryotic adaptive immune systems that provide protection against bacteriophage (phage) and other parasites. Little is known about how CRISPR-Cas systems are regulated, preventing prediction of phage dynamics in nature and manipulation of phage resistance in clinical settings. Here
Yefei Zhou et al.
Poultry science, 98(7), 2790-2799 (2019-02-20)
Baicalein, the main flavonoid extracted from the root of Scutellaria baicalensis Georgi, has been demonstrated to exert multiple pharmacological effects, and thus could be utilized as a potential feed additive in broiler chickens. This study evaluated the effects of broiler
D E Shieh et al.
Anticancer research, 20(5A), 2861-2865 (2000-11-04)
Xanthine oxidase inhibitors are known to be therapeutically useful for the treatment of hepatitis and brain tumor. Baicalein, baicalin and wogonin, isolated from Scutellaria rivularis, have been reported to exhibit a strong activity on xanthine oxidase inhibition. In this study
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 465119-500MG | 04061832356846 |
| 465119-100MG | 04061832356822 |