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Merck
CN

47627

Fmoc-Gly-OH

≥98.0% (T)

别名:

Fmoc-甘氨酸

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关于此项目

经验公式(希尔记法):
C17H15NO4
化学文摘社编号:
分子量:
297.31
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
249-373-3
MDL number:
Beilstein/REAXYS Number:
2163967
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Quality Level

assay

≥98.0% (T)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

174-175 °C (lit.), 174-178 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)CNC(=O)OCC1c2ccccc2-c3ccccc13

InChI

1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)

InChI key

NDKDFTQNXLHCGO-UHFFFAOYSA-N

Application

  • Efficient Fmoc-Protected Amino Ester Hydrolysis Using Green Calcium (II) Iodide as a Protective Agent:研究在Fmoc-保护氨基酯的水解反应中采用环境友好的碘化钙,提高反应效率和可持续性(R Binette, M Desgagné, C Theaud, PL Boudreault - Molecules, 2022)。文章链接
  • α/β-Chimera peptide synthesis with cyclic β-sugar amino acids: the efficient coupling protocol:研究采用环β-糖氨基酸更好地合成α/β-嵌合肽,说明在药物化学的多肽设计中具有重要应用潜力(A Nagy, V Goldschmidt Gőz, I Pintér, V Farkas - Amino acids, 2019)。文章链接
  • MS, CD, and FT-IR characterization of five newly synthesized histidine-containing Ala-and Gly-based peptides:详细鉴定了新的含组氨酸多肽,说明对肽类药物开发有重要意义的技术(M Murariu, L Ion, CI Ciobanu, BA Petre - Rev. Roum Chem., 2017)。文章链接
  • Efficient method for the concentration determination of fmoc groups incorporated in the core-shell materials by Fmoc–glycine:详细说明了测定核壳材料中fmoc基团浓度的高效方法,对于先进功能材料的设计具有重要意义(E Szczepańska, B Grobelna, J Ryl, A Kulpa - Molecules, 2020)。文章链接
  • Circular aqueous fmoc/t‐bu solid‐phase peptide synthesis:探索了固相多肽合成的循环水相新方法,可能提供了更高效环保的肽合成方法(J Pawlas, JH Rasmussen - ChemSusChem, 2021)。文章链接

Other Notes

糖类β-糖胺的fmoc-甘氨酸偶联,可用于低聚糖的分馏和新糖结合物的形成。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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分析证书(COA)

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Jing Fu et al.
Journal of hazardous materials, 368, 186-196 (2019-01-25)
Methyl-triclosan (MTCS), as a biodegradation product from antibacterial triclosan (TCS), has been detected in water catchments, and it has also been verified to accumulate in biota due to its hydrophobicity. There is a lack, however, of toxicity studies on MTCS
P H Naccache et al.
Blood, 84(2), 616-624 (1994-07-15)
The control of the adhesive properties of human neutrophils is an essential element of their defense function. One level at which this control is exerted involves the upregulation of the surface expression of beta 2-integrins. In this study, we have
Mario Fernández-Fernández et al.
Journal of mass spectrometry : JMS, 51(10), 980-987 (2016-07-09)
We have developed a novel, rapid and easy calculation procedure for Mass Isotopomer Distribution Analysis based on multiple linear regression which allows the simultaneous calculation of the precursor pool enrichment and the fraction of newly synthesized labelled proteins (fractional synthesis)



全球贸易项目编号

货号GTIN
47627-1KG-F04061826222720
47627-5G-F04061832362311
47627-250G-F04061832362298
47627-50G-F04061832362304