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关于此项目
经验公式(希尔记法):
C39H34N2O5
化学文摘社编号:
分子量:
610.70
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
4343953
MDL number:
产品名称
FFmoc-N-三苯甲基-L-谷氨酰胺, ≥98.0% (HPLC)
Quality Level
assay
≥98.0% (HPLC)
form
powder
optical activity
[α]/D -14.0±1.5°, c = 1% in DMF
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
SMILES string
OC(=O)[C@H](CCC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
InChI
1S/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)25-24-35(37(43)44)40-38(45)46-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34/h1-23,34-35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t35-/m0/s1
InChI key
WDGICUODAOGOMO-DHUJRADRSA-N
General description
Fmoc-Gln(Trt)-OH 也称 Nα-Fmoc-Nδ-三苯甲基-L-谷氨酰胺,它是 Fmoc 保护的氨基酸衍生物,可用作合成肽的试剂。 由于谷氨酰胺受到三苯甲基保护,因此可以防止在反应中出现不需要的取代产物。
Application
Fmoc-Gln(Trt)-OH可用作Fmoc 固相肽合成的原料,用于合成fellutamide B 和 fellutamide B的N-辛酰基类似物。
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存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
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Serpin proteins irreversibly inhibit serine proteases, but only a small part of the serpin reactive-center loop (RCL) is responsible for the initial protein-protein interaction (PPI). To develop peptidic protease inhibitors, kallikrein-related peptidases 7 (KLK7) and 5 (KLK5) were chosen. Firstly
Marcus Pickhardt et al.
Current Alzheimer research, 14(7), 742-752 (2017-02-06)
Anti-aggregation drugs play an important role in therapeutic approaches for Alzheimer's disease. We have previously developed a number of compounds that are able to inhibit the pathological aggregation of Tau protein. One common obstacle to application is the limited penetration
Fatemeh Zabihi et al.
Journal of controlled release : official journal of the Controlled Release Society, 242, 35-41 (2016-07-30)
Nanogels offer many unique features rendering them as very attractive candidates for drug delivery. However, for their applications the loading capacity and specific encapsulation, in particular for hydrophobic drugs, in a complex media are two critical factors. In this work
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 47674-25G-F | 04061832372730 |
| 47674-5G-F | 04061832372747 |
| 47674-100G-F | 04061832372723 |
| 47674-1KG-F | 04061826222805 |