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Merck
CN

479306

二氯化二胺(II)

≥99.9% trace metals basis

别名:

顺铂, 顺-二氯二氨基铂(II), 顺式-二胺二氯铂, 顺氯氨铂

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关于此项目

线性分子式:
Pt(NH3)2Cl2
化学文摘社编号:
分子量:
300.05
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
EC Number:
239-733-8
MDL number:
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Quality Level

assay

≥99.9% trace metals basis

reaction suitability

core: platinum, reagent type: catalyst

mp

270 °C (lit.)

antibiotic activity spectrum

neoplastics

mode of action

DNA synthesis | interferes

SMILES string

N.N.Cl[Pt]Cl

InChI

1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2

InChI key

LXZZYRPGZAFOLE-UHFFFAOYSA-L

Application

二氯化二胺(II)可用作模型药物以测试药物递送中各种药物载体的效率。
高活性化疗剂,可用于预防睾丸癌的进展。

Biochem/physiol Actions

强效的铂基抗肿瘤剂。与 DNA 二核苷酸 d(pGpG) 形成细胞毒性加合物,诱导链内交联。


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

target_organs

Respiratory system

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Classifications

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3



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分析证书(COA)

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全球贸易项目编号

货号GTIN
479306-50G04061833411339
479306-1G04061835555208
479306-5G04061832373287