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482609

N-[(2S,3R)-3-氨基-2-羟基-4-苯基丁酰基]-L-亮氨酸

Name: N-[(2S,3R)-3-氨基-2-羟基-4-苯基丁酰基]-<SC>L</SC>-亮氨酸
Brand: ALDRICH

97%

别名:

([2S,3R]-3-氨基-2-羟基-4-苯基丁酰基)-L-亮氨酸

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关于此项目

线性分子式:

(CH₃)₂CHCH₂CH[NHCOCH(OH)CH(NH₂)CH₂C₆H₅]CO₂H

化学文摘社编号:

58970-76-6

分子量:

308.37

NACRES:

NA.22

PubChem Substance ID:

24871835

UNSPSC Code:

12352209

EC Number:

261-529-2

MDL number:

MFCD00083262

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属性

Quality Level

100

assay

97%

form

powder or crystals

optical activity

[α]20/D −11°, c = 1 in 1 M NaOH

reaction suitability

reaction type: solution phase peptide synthesis

mp

245 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O

InChI

1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1

InChI key

VGGGPCQERPFHOB-RDBSUJKOSA-N

Gene Information

human ... ANPEP(290), DPP4(1803)
mouse ... Rnpep(215615)
rat ... Mme(24590)

说明

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

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Leucine aminopeptidases (LAP; EC 3.4.11.1) are a group of metalloexopeptidases, which catalyze the sequential removal of leucine amino acids from the N-termini of the polypeptides or proteins. In this study, we identified two novel genes that encode LAPs of Clonorchis

Influence of bestatin, an inhibitor of aminopeptidases, on T and B lymphocyte subsets in mice.

M Lis et al.

Polish journal of veterinary sciences, 14(3), 393-403 (2011-10-01)

Bestatin, a low-molecular weight dipeptide, is a potent inhibitor of aminopeptidase N which has been demonstrated to have antitumor and immunomodulatory effects. The effects of bestatin (10, 1 and 0.1 mg/kg) administered intraperitoneally once, five or ten times to mice

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货号	GTIN
482609-500MG	04061832594989