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49960

1-油酰基-rac-甘油

Name: 1-油酰基-<I>rac</I>-甘油
Brand: ALDRICH

technical, ~40% (TLC)

别名:

1-(顺-9- 十八烯酰基)-rac-甘油, rac-甘油 1-单油酸酯, DL-α-甘油单油酸酯, 甘油顺-9-十八烯酰基, 甘油单油酸酯

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关于此项目

线性分子式:

CH₃(CH₂)₇CH=CH(CH₂)₇COOCH₂CHOHCH₂OH

化学文摘社编号:

111-03-5

分子量:

356.54

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

57651231

EC Number:

203-827-7

Beilstein/REAXYS Number:

1728976

MDL number:

MFCD00042735

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属性

description

non-ionic

Quality Level

100

grade

technical

concentration

~40% (TLC)

impurities

15-40% diglyceride, 15-40% triglyceride

functional group

ester, hydroxyl

SMILES string

O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO

InChI

1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI key

RZRNAYUHWVFMIP-KTKRTIGZSA-N

说明

General description

1-油酰基-rac-甘油通常称为甘油单油酸酯（MO）。它是由甘油主链和烃链组成的两亲性分子。

Application

Bovine Serum Albumin (BSA) Encapsulated in DODAB: MO (1: 2) Liposomes for Targeted Drug Delivery: Development and Characterization：开发含有双十八烷基二甲基溴化铵(DODAB)和1-油酰-外消旋甘油的脂质体用于靶向药物递送(A VAN DIJCK, 2014)。
An Innovative Nanocarrier for Neuroprotection：研究在DODAB和1-油酰-外消旋甘油(MO)(1:2)组成的纳米载体中包封姜黄素的治疗好处(T Soares, No Date Provided)。
Supporting Information Light-responsive Molecular Release from Cubosomes using Swell-Squeeze Lattice Control：讨论含1-油酰-外消旋甘油结构的分子释放机制(BE Jones et al., No Date Provided)。
The Potential of Macroporous Silica—Nanocrystalline Cellulose Combination for Formulating Dry Emulsion Systems with Improved Flow Properties: A DoE Study：详述混有1-油酰-外消旋甘油的干乳系统制剂，用于改善药物应用(M Pohlen, L Pirker, R Dreu, 2021)。
The Metabolomic Bioenergetic Signature of Opa1-Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency：代谢变化分析，提及1-油酰-外消旋甘油等物质的作用(C Bocca et al., 2018)。

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存储类别

10 - Combustible liquids

flash_point_f

309.2 °F - closed cup

flash_point_c

154.0 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

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Structures of human ENT1 in complex with adenosine reuptake inhibitors.

Nicholas J Wright et al.

Nature structural & molecular biology, 26(7), 599-606 (2019-06-27)

The human equilibrative nucleoside transporter 1 (hENT1), a member of the SLC29 family, plays crucial roles in adenosine signaling, cellular uptake of nucleoside for DNA and RNA synthesis, and nucleoside-derived anticancer and antiviral drug transport in humans. Because of its

Reconstitutable spray dried ultra-fine dispersion as a robust platform for effective oral delivery of an antihyperlipidemic drug.

Mona Basha et al.

International journal of pharmaceutics, 532(1), 478-490 (2017-09-20)

The current article highlights the application of spray drying technique to produce an ultra-fine powder encapsulating the antihyperlipidemic drug, atorvastatin calcium (ATV). First, ATV was dissolved in an emulsion formulation, and different carriers (pectin, alginate, chitosan HCl and hydroxypropylmethyl cellulose)

Monoolein: a magic lipid?

Kulkarni CV, et al.

Physical Chemistry Chemical Physics, 13(8), 3004-3021 (2011)

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全球贸易项目编号

货号	GTIN
49960-1KG	04061832422046
49960-10ML-KC	04061837332579
49960-250G	04061832422053