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Merck
CN

531480

N-芴甲氧羰基-L-丙氨酸

95%, for peptide synthesis

别名:

N-芴甲氧羰基-L-丙氨酸, Fmoc-L-丙氨酸

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关于此项目

经验公式(希尔记法):
C18H17NO4
化学文摘社编号:
分子量:
311.33
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
252-660-6
MDL number:
Beilstein/REAXYS Number:
2225975
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产品名称

N-芴甲氧羰基-L-丙氨酸, 95%

Quality Level

assay

95%

optical activity

[α]20/D −18°, c = 1 in DMF

reaction suitability

reaction type: C-H Activation, reaction type: Fmoc solid-phase peptide synthesis, reagent type: ligand
reaction type: Peptide Synthesis

mp

147-153 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc, amine, carboxylic acid

storage temp.

2-8°C

SMILES string

C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1

InChI key

QWXZOFZKSQXPDC-NSHDSACASA-N

General description

Fmoc-Ala-OH又称为Fmoc-L-丙氨酸, 在Fmoc固相肽合成中起多种作用。

Application

Fmoc-Ala-OH的一般用途:
  • 作为制备三唑肽和氮杂肽的构件
  • 通过标准Fmoc固相肽合成法合成双阳离子卟啉肽
  • 不经过氮杂环丙烷化作用,将曼尼希加合物转化为α-卤化酰胺


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Leixia Mei et al.
Organic & biomolecular chemistry, 17(4), 939-944 (2019-01-11)
We report the synthesis and self-assembly of fluorescent peptide amphiphiles (NBD-PA) composed of a fluorescent NBD probe and a peptide derivative VVAADD with a C12-alkyl-chain as the linker (NBD-C12-VVAADD). The self-assembly of NBD-PA formed beta-sheet structures at neutral pH in



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