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702153

羟基磷灰石

nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)

别名:

Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate

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关于此项目

线性分子式:
[Ca5(OH)(PO4)3]x
化学文摘社编号:
12167-74-7
分子量:
502.31
NACRES:
NA.23
PubChem Substance ID:
329762350
UNSPSC Code:
12352302
MDL number:
MFCD00010904
Form:
dispersion, nanoparticles
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Quality Level

100

form

dispersion, nanoparticles

contains

≤0.025 wt. % dispersant (non-metal based)

concentration

10 wt. % in H2O

surface area

14.3 m2/g , typical

particle size

<200 nm (BET)

pH

4-6

density

1.038 g/mL at 25 °C

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

General description

羟基磷灰石(HAP)是一种骨传导生物陶瓷材料，它具有独特的性能可以直接与活体组织结合。它可以通过多种技术制备，如溶液-凝胶法、水热法、多重乳化法、仿生沉积法和电沉积法。

Application

羟基磷灰石可被用于：
  • 一种替代骨的植入材料，因为其化学成分与 骨中无机盐成分相似且有骨诱导特性。
  • 基因和药物载体，因为它具有封装能力和 对许多药物、蛋白有亲和力。
  • 对pH响应的微粒乳化剂。

Features and Benefits

  • 生物相容的
  • 骨传导的
  • 在 胜利条件下稳定
  • 高机械强度高强度

Legal Information

Engi-Mat Co.产品。

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCP8250
MKCN6392
MKCL6094
MKBW5896V
MKBR8934V

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商品

Nanomaterials for Biomedical Applications

Nanoparticles can be used for applications such as growing cells for tissue engineering, nanocomposites used in orthopedics, and miniaturized sensors for DNA, pathogens, and chemicals.

Liam M Grover et al.
Biomaterials, 34(28), 6631-6637 (2013-06-12)
Pyrophosphate ions are both inhibitors of HA formation and substrates for phosphatase enzymes. Unlike polyphosphates their hydrolysis results simultaneously in the complete loss of mineral formation inhibition and a localised elevation in orthophosphate ion concentration. Despite recent advances in our
W Zhang et al.
Journal of dental research, 92(12), 1136-1141 (2013-10-08)
Stem cell-based bone tissue engineering has been recognized as a new strategy for maxillary sinus floor elevation. More rapid bone formation may enhance this technique when simultaneous dental implant placement is desired. Adipose tissue-derived stem cells (ADSCs) and bone marrow
Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
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全球贸易项目编号

货号GTIN
702153-25ML04061832820743