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Merck
CN

719889

Resomer® RG 502,聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide 50:50, ester terminated, Mw 7,000-17,000

别名:

RESOMER® RG 502

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关于此项目

线性分子式:
[C3H4O2]x[C2H2O2]y
NACRES:
NA.23
UNSPSC Code:
12162002
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Quality Level

form

amorphous

feed ratio

lactide:glycolide 50:50

mol wt

Mw 7,000-17,000

degradation timeframe

<3 months

viscosity

0.16-0.24 dL/g, 0.5 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

transition temp

Tg 42-46 °C

shipped in

wet ice

storage temp.

2-8°C

Application

Resomer® RG 502可用于制备基于PLGA的纳米 药物递送系统,用于抗炎药物6-溴靛玉红-3′-甘油肟醚(6BIGOE)。

它还可用于制备盐酸纳洛酮递送的控制释放。

Features and Benefits

  • 生物相容性
  • 生物可降解
  • 可加工成几乎任何形状和尺寸
  • 机械性能可调

Legal Information

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

商业生物材料已停滞不前超过30年的时间,因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局(FDA)批准的记录,一直在可吸收生物材料领域占据主导地位。

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

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Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may



全球贸易项目编号

货号GTIN
719889-5G04061832855448
719889-1G04061832855431