761591
(4-(1,2,4,5-四嗪-3-基)苯基)甲胺 盐酸盐
95%
别名:
H-Tz-Bz-NH3Cl 盐酸盐, 苄氨基四嗪 盐酸盐
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关于此项目
经验公式（希尔记法）:
C9H9N5 · xHCl
化学文摘社编号:
分子量:
187.20 (free base basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
Assay:
95%
Form:
solid
Quality Level
assay
95%
form
solid
reaction suitability
reaction type: click chemistry, reagent type: linker
mp
206-225 °C (decomposition)
functional group
amine
storage temp.
−20°C
SMILES string
NCC1=CC=C(C2=NN=CN=N2)C=C1.[H]Cl
InChI
1S/C9H9N5.ClH/c10-5-7-1-3-8(4-2-7)9-13-11-6-12-14-9;/h1-4,6H,5,10H2;1H
InChI key
FAAUXGMWUKVOPI-UHFFFAOYSA-N
General description
4-(1,2,4,5-四嗪-3-基)苯基)甲胺是一种1,2,4,5-四嗪衍生物，能够与张力较大的烯烃发生[4+2] Diels-Alder环加成反应，这使其在生物正交标记和细胞检测应用中非常实用。
Application
胺官能化四嗪可用于反电子需求Diels-Alder环加成反应。四嗪将与张力较大的烯烃反应，如反式环辛烯、降冰片烯和环丙烯，产生稳定的共价键。已证明四嗪可用于许多生物成像和生物共轭应用的生物正交反应。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
实验方案
Protocol for GC Analysis of Bacterial Acid Methyl Esters (BAMEs) on Equity®-1
Thermally Induced Silane Dehydrocoupling on Silicon Nanostructures.
Kim D, et al.
Angewandte Chemie (International Edition in English), 55(22), 6423-6427 (2016)
Synthesis and evaluation of a series of 1, 2, 4, 5-tetrazines for bioorthogonal conjugation
Karver MR, et al.
Bioconjugate Chemistry, 22(11), 2263-2270 (2011)
A Bone-Seeking trans-Cyclooctene for Pretargeting and Bioorthogonal Chemistry: A Proof of Concept Study Using 99mTc-and 177Lu-Labeled Tetrazines.
Yazdani A, et al.
Journal of Medicinal Chemistry, 59(20), 9381-9389 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 761591-10MG | 04061833241851 |
| 761591-25MG | 04061833241868 |