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792632

异氟醚

Name: 异氟醚
Brand: ALDRICH

别名:

异氟醚, 1-氯-1-（二氟甲氧基）-2,2,2-三氟乙烷, 1-氯-2,2,2-三氟乙基二氟甲醚

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关于此项目

经验公式（希尔记法）:

C₃H₂ClF₅O

化学文摘社编号:

26675-46-7

分子量:

184.49

NACRES:

NA.22

PubChem Substance ID:

329768352

UNSPSC Code:

12352100

EC Number:

247-897-7

MDL number:

MFCD00066609

Form:

liquid

Quality level:

100

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属性

vapor pressure

238 mmHg ( 20 °C)

Quality Level

100

form

liquid

refractive index

n20/D 1.302

bp

48.5 °C

density

1.510 g/mL at 25 °C

functional group

chloro, ether, fluoro

storage temp.

2-8°C

SMILES string

FC(F)OC(Cl)C(F)(F)F

InChI

1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H

InChI key

PIWKPBJCKXDKJR-UHFFFAOYSA-N

Gene Information

说明

General description

异氟醚是一种氟化甲醚和安氟醚异构体。美国联邦药物管理局已经批准了其作为挥发性麻醉剂的用途，用于引起并维持全身麻醉。

Application

异氟烷是一种挥发性麻醉剂，主要用于研究其与生物系统的相互作用。

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pictograms

GHS07

signalword

Warning

hcodes

H336

pcodes

P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501

Hazard Classifications

STOT SE 3

target_organs

Central nervous system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Anesthesiology, 112(4), 834-841 (2010)

Increased Microglial Activity, Impaired Adult Hippocampal Neurogenesis, and Depressive-like Behavior in Microglial VPS35-Depleted Mice.

Joanna Ruth Appel et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(26), 5949-5968 (2018-06-02)

Vacuolar sorting protein 35 (VPS35) is a critical component of retromer, which is essential for selective endosome-to-Golgi retrieval of membrane proteins. VPS35 deficiency is implicated in neurodegenerative disease pathology, including Alzheimer's disease (AD). However, exactly how VPS35 loss promotes AD

Isoflurane provides neuroprotection in neonatal hypoxic ischemic brain injury.

Sherrefa R Burchell et al.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 61(7), 1078-1083 (2013-07-26)

Isoflurane is a volatile anesthetic that is widely used clinically as an inhalational anesthetic. In recent years, several studies have indicated that isoflurane has neuroprotective properties. This has led to the beneficial effects of isoflurane being analyzed in both cell

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全球贸易项目编号

货号	GTIN
792632-1G	04061826004326
792632-250MG	04061832951003