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关于此项目
经验公式(希尔记法):
C12H14N2O2
化学文摘社编号:
分子量:
218.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
248-157-6
MDL number:
Assay:
97%
Form:
solid
Quality Level
assay
97%
form
solid
mp
250 °C (dec.) (lit.)
functional group
amine, carboxylic acid
SMILES string
Cn1cc(CC(N)C(O)=O)c2ccccc12
InChI
1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)
InChI key
ZADWXFSZEAPBJS-UHFFFAOYSA-N
Application
1-甲基- DL -色氨酸是吲哚胺 2,3 双加氧酶-1 (IDO1) 的竞争性抑制剂,已用于研究炎症诱导的小鼠抑郁症和合胞病毒诱导的毛细支气管炎。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Motivational changes that develop in a mouse model of inflammation-induced depression are independent of indoleamine 2, 3 dioxygenase.
Vichaya, Elisabeth G et al.
Neuropsychopharmacology (2018)
Neda Milosavljevic et al.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 23(8), 1040-1050 (2017-05-10)
Mesenchymal stem cells (MSCs) are, due to immunomodulatory characteristics, considered as novel agents in the treatment of immune-mediated acute liver failure. Although it is known that MSCs can regulate activation of T lymphocytes, their capacity to modulate function of neutrophils
Seung-Ha Yang et al.
Experimental & molecular medicine, 41(5), 315-324 (2009-03-25)
Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on T cells. Irradiated MSCs co-cultured with either na?ve or pre-activated
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860646-250MG | 04061833483947 |
| 860646-1G | 04061833033449 |