900865
4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride
≥95%
别名:
Formyl sulfonyl fluoride TMS-Alkyne, Probe building block
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Assay:
≥95%
Form:
powder or crystals
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry
storage temp.
−20°C
SMILES string
O=CC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1
Application
4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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商品
在与K. Barry Sharpless及其同事合作后，Sigma-Aldrich现可提供各种磺酰氟试剂，这些试剂经历了“Click II”反应。
In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 900865-50MG | 04061833251317 |