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关于此项目
经验公式(希尔记法):
C27H36N6O10
化学文摘社编号:
分子量:
604.61
UNSPSC Code:
12352108
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
powder or crystals
Quality Level
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry, reagent type: linker
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(NCC1=CC=C(C2=NN=CN=N2)C=C1)CCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O
InChI
1S/C27H36N6O10/c34-23(28-19-21-1-3-22(4-2-21)27-31-29-20-30-32-27)7-9-38-11-13-40-15-17-42-18-16-41-14-12-39-10-8-26(37)43-33-24(35)5-6-25(33)36/h1-4,20H,5-19H2,(H,28,34)
InChI key
DUPHIQYIPUTDJS-UHFFFAOYSA-N
General description
四嗪-PEG5-NHS 酯具有可与伯胺反应的 N-羟基琥珀酰亚胺(NHS)酯和可与反式环辛烯反应的四嗪。氢取代的四嗪表现出异常快的动力学,与甲基取代的四嗪相比通常快至少 10 倍。亲水性聚乙二醇(PEG)间隔臂大大提高了该试剂的水溶性。
Application
四嗪-PEG5-NHS 酯(Tz-PEG5-NHS)可用于点击化学应用,例如利用选择性四嗪-反式-环辛烯(Tz-TCO)连接制备壳聚糖-聚丙烯酰胺微球,以及通过点击反应构建铜 64 放射性标记抗体。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
为您的生化或生物共轭研究选择合适的交联剂可能具有挑战性。我们的选择指南可以帮助您找到最适合您应用的交联剂。
Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.
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We report a click-chemistry based modular strategy for antibody labeling with (64)Cu (t1/2 = 12.7 h; β(+) 0.656 MeV, 17.4%; β(-) 0.573 MeV, 39%; EC 43%) under ambient condition utilizing a cross-bridged tetraazamacrocyclic (CB-TE2A) analogue, which otherwise requires harsh conditions
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 900913-50MG | 04061833251409 |