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Merck
CN

925136

4,6-Dimethyl-2-(methylsulfinyl)-3-nitropyridine

别名:

2-Sulfonylpyridine, Cysteine-reactive electrophile, SNAr probe

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关于此项目

经验公式(希尔记法):
C8H10N2O3S
化学文摘社编号:
分子量:
214.24
MDL number:
NACRES:
NA.22
UNSPSC Code:
12352200
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reaction suitability

reagent type: chemical modification reagent

Quality Level

storage temp.

2-8°C

Application

4,6-Dimethyl-2-(methylsulfinyl)-3-nitropyridine is a sulfoxide-containing fragment for covalent ligand discovery via cysteine labeling as demonstrated by Zamboldo and coworkers. Fragment electrophiles are useful in chemoproteomic and ligandability studies for both traditionally druggable proteins as well as ″undruggable,″ or difficult-to-target, proteins.

Related useful products may include cysteine fragment KB02 (912131), IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059).


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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全球贸易项目编号

货号GTIN
925136-100MG04065267468655
925136-50MG04065267468662