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927562

MSOD-alkyne

≥95%

别名:

2-(Methylsulfonyl)-5-(4-(prop-2-yn-1-yloxy)phenyl)-1,3,4-oxadiazole

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关于此项目

经验公式（希尔记法）:
C12H10N2O4S
化学文摘社编号:
2550395-07-6
分子量:
278.28
MDL number:
MFCD29904541
NACRES:
NA.22
UNSPSC Code:
12352101
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Quality Level

100

assay

≥95%

form

powder

storage temp.

−20°C

Application

MSOD-alkyne is a probe that can be used to label cysteines through nucleophilic aromatic substitution. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitative applications . The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis . Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow .

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Profiling the proteome-wide selectivity of diverse electrophiles
Zanon, et al
ChemRxiv : the preprint server for chemistry (2021)
Isotopically Labeled Desthiobiotin Azide (isoDTB) Tags Enable Global Profiling of the Bacterial Cysteinome
Zanon, et al
Angewandte Chemie (International Edition in English), 2829-2836 (2020)

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货号GTIN
927562-50MG04065268057360