927600
BrBT-alkyne
≥95%
别名:
2-Bromo-N-(prop-2-yn-1-yl)benzo[d]thiazole-6-carboxamide
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关于此项目
经验公式（希尔记法）:
C11H7BrN2OS
化学文摘社编号:
分子量:
295.16
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.22
Quality Level
assay
≥95%
form
powder
storage temp.
−20°C
SMILES string
BrC1=NC2=CC=C(C(NCC#C)=O)C=C2S1
InChI
1S/C11H7BrN2OS/c1-2-5-13-10(15)7-3-4-8-9(6-7)16-11(12)14-8/h1,3-4,6H,5H2,(H,13,15)
InChI key
MRYSQSUDZPBHGP-UHFFFAOYSA-N
Application
BrBT-alkyne is a probe that can be used to lable cysteines through nucleophilic aromatic substitution. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitave applications (Zanon et al. 2021). The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis (Zanon et al. 2020). Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow (Weerapana et al. 2010, Backus et al. 2016).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Isotopically Labeled Desthiobiotin Azide (isoDTB) Tags Enable Global Profiling of the Bacterial Cysteinome.
Zanon P R A, et al.
Angewandte Chemie (International Edition in English), 2829-2836 (2020)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 927600-50MG | 04065268032183 |