930628
VH 032 amide-alkyl C3-acid
≥95%
别名:
(4R), (S,R,S)-AHPC-CO-C3-acid, L-Prolinamide, N-(4-carboxy-1-oxobutyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C27H36N4O6S
化学文摘社编号:
分子量:
544.66
UNSPSC Code:
51471602
NACRES:
NA.21
MDL number:
Assay:
≥95%
Form:
powder
ligand
VH032
Quality Level
assay
≥95%
form
powder
functional group
carboxylic acid
storage temp.
2-8°C
SMILES string
C([C@@H](NC(CCCC(O)=O)=O)C(C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
InChI key
FKGREQKARAJLQH-JXALWOEJSA-N
Application
VH 032 amide-alkyl C3-acid is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal carboxyl group, allowing rapid conjugation of amine containing linkers. A basic building block for development of a protein degrader library.
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
Other Notes
Targeted Protein Degradation by Small Molecules
Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 930628-50MG | 04065268894231 |