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D126608

普鲁泊福

Name: 普鲁泊福
Brand: ALDRICH

97%

别名:

2,6-双(1-甲基乙基)苯酚, 普鲁泊福

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关于此项目

线性分子式:

[(CH₃)₂CH]₂C₆H₃OH

化学文摘社编号:

2078-54-8

分子量:

178.27

NACRES:

NA.22

PubChem Substance ID:

24278001

UNSPSC Code:

12352100

EC Number:

218-206-6

MDL number:

MFCD00008885

Assay:

97%

Form:

liquid

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属性

vapor pressure

5.6 mmHg ( 100 °C)

Quality Level

100

assay

97%

form

liquid

refractive index

n20/D 1.514 (lit.)

bp

256 °C/764 mmHg (lit.)

mp

18 °C (lit.)

density

0.962 g/mL at 25 °C (lit.)

SMILES string

CC(C)c1cccc(C(C)C)c1O

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

InChI key

OLBCVFGFOZPWHH-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)
rat ... Gabra2(29706)

说明

General description

2,6-二异丙基苯酚（一种强疏水取代苯酚）是一种新型静脉麻醉剂。已研究 2,6-二异丙基苯酚（异丙酚）的抗氧化属性。2,6-二异丙基苯酚是一种有效的静脉注射催眠药，广泛用于麻醉诱导和维持以及重症监护病房的镇静。用于全身麻醉的诱导和维持。

Application

2,6-二异丙基苯酚是研究其对离体大鼠肝线粒体氧化磷酸化作用的合适试剂。是制备双（2,6-二异丙基苯氧基）双（2-甲基-8-喹啉）钛 (IV) 配合物的合适试剂。

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pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Human brain sodium channels as one of the molecular target sites for the new intravenous anaesthetic propofol (2,6-diisopropylphenol).

C Frenkel et al.

European journal of pharmacology, 208(1), 75-79 (1991-09-12)

Single sodium channels from human brain cortex tissue were incorporated into voltage-clamped planar lipid bilayers in the presence of batrachotoxin and studied with various doses of the new anaesthetic compound propofol (2,6-diisopropylphenol). Propofol was found to depress two major sodium

The antioxidant potential of propofol (2,6-diisopropylphenol).

P G Murphy et al.

British journal of anaesthesia, 68(6), 613-618 (1992-06-01)

We have examined in vitro the antioxidant properties of 2,6-diisopropylphenol. In studies using electron spin resonance spectroscopy we have demonstrated that 2,6-diisopropylphenol acts as an antioxidant by reacting with free radicals to form a phenoxyl radical--a property common to all

Mechanisms of inhibition and uncoupling of respiration in isolated rat liver mitochondria by the general anesthetic 2,6-diisopropylphenol.

M Rigoulet et al.

European journal of biochemistry, 241(1), 280-285 (1996-10-01)

We investigated the effects of 2,6-diisopropylphenol on oxidative phosphorylation of isolated rat liver mitochondria. Diisopropylphenol strongly inhibits state-3 and uncoupled respiratory rates, when glutamate and malate are the substrates, as a direct consequence of the limitation of electron transfer at

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全球贸易项目编号

货号	GTIN
D126608-100G	04061833559192
D126608-5G	04061833559208