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G11950

鸟嘌呤

Name: 鸟嘌呤
Brand: ALDRICH

98%

别名:

2-乌嘌呤, 2-氨基-1，7-二氢-6H-嘌呤-6-酮, 2-氨基-6-羟基嘌呤

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关于此项目

经验公式（希尔记法）:

C₅H₅N₅O

化学文摘社编号:

73-40-5

分子量:

151.13

UNSPSC Code:

12352005

NACRES:

NA.22

PubChem Substance ID:

24895050

EC Number:

200-799-8

Beilstein/REAXYS Number:

9680

MDL number:

MFCD00071533

Assay:

98%

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属性

Quality Level

200

assay

98%

mp

>300 °C (lit.)

solubility

hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green

SMILES string

NC1=Nc2[nH]cnc2C(=O)N1

InChI

1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

InChI key

UYTPUPDQBNUYGX-UHFFFAOYSA-N

说明

General description

腺嘌呤、胞嘧啶、胸腺嘧啶和鸟嘌呤是核酸DNA和RNA中发现的四种主要核碱基。鸟嘌呤是嘌呤衍生物。据报道，它组装成类似大环的方形平面基团，其中碱基通过氢键相互作用。在DNA和RNA中，据报道，在钠离子或钾离子存在下，一系列鸟嘌呤碱基形成稳定的四链螺旋。已经在各种碳电极的水性介质中研究了鸟嘌呤的电化学氧化。它在生理条件下与过氧亚硝酸盐反应，得到 8-硝基胍。

Application

鸟嘌呤是用于研究鸟嘌呤和腺嘌呤的电化学氧化机理的合适试剂，使用玻碳微电极和循环和微分脉冲伏安法。它可用于制备混合序列肽核酸（PNA）单体。

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

DISCOVER Bioactive Small Molecules for Neuroscience

Electrochemical oxidation mechanism of guanine and adenine using a glassy carbon microelectrode.

A M Oliveira-Brett et al.

Bioelectrochemistry (Amsterdam, Netherlands), 55(1-2), 61-62 (2002-01-12)

The electrochemical oxidation mechanism of guanine and adenine was investigated using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It is pH-dependent and the electron transfer process occurs in consecutive steps with the formation of strongly adsorbed dimers

The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution.

K Phillips et al.

Journal of molecular biology, 273(1), 171-182 (1997-11-21)

In both DNA and RNA, stretches of guanine bases can form stable four-stranded helices in the presence of sodium or potassium ions. Sequences with a propensity to form guanine tetraplexes have been found in chromosomal telomers, immunoglobulin switch regions, and

Electrochemical oxidation of guanine: electrode reaction mechanism and tailoring carbon electrode surfaces to switch between adsorptive and diffusional responses.

Qian Li et al.

The journal of physical chemistry. B, 114(21), 7423-7428 (2010-05-08)

The electrochemical oxidation of guanine is studied in aqueous media at various carbon electrodes. Specifically edge plane pyrolytic graphite (EPPG), basal plane pyrolytic graphite (BPPG), and highly ordered pyrolytic graphite (HOPG) were used, and the voltammetry was found to vary

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全球贸易项目编号

货号	GTIN
G11950-100G	04061838357830
G11950-10G	04061838671608
G11950-25G	04061833627983