N8141
4-硝基喹啉 N -氧化物
≥98%
别名:
1-氧化-4-硝基喹啉, 4-NQO
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关于此项目
经验公式（希尔记法）:
C9H6N2O3
化学文摘社编号:
分子量:
190.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-281-1
Beilstein/REAXYS Number:
165756
MDL number:
Assay:
≥98%
assay
≥98%
color
yellow to brown
mp
154-156 °C (lit.)
solubility
acetone: soluble, clear to hazy
storage temp.
−20°C
SMILES string
[O-][N+](=O)c1cc[n+]([O-])c2ccccc12
InChI
1S/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H
InChI key
YHQDZJICGQWFHK-UHFFFAOYSA-N
General description
4-硝基喹啉N-氧化物是一种广泛应用于化学研究和开发的喹啉衍生物。
Application
4-硝基喹啉 N-氧化物已被用作模型化合物以研究其致癌作用。
Biochem/physiol Actions
在试验条件下可诱发皮肤和肺肿瘤。
signalword
Danger
hcodes
Hazard Classifications
Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
商品
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.
The antimutagenic effect of monoterpenes against UV-irradiation-, 4NQO-and t-BOOH-induced mutagenesis in coli.
Nikolic B, et al.
Archives of Biological Sciences, 63(1), 117-128 (2011)
Ye Du et al.
Environment international, 135, 105369-105369 (2019-12-17)
Effluents from wastewater treatment plants (WWTPs) may contain various pollutants with potential toxic effects. Ozonation is widely applied to purify wastewater, which may influence the toxicity and water quality indices simultaneously. The main goal of this study was to reveal
MTA1 promotes tumorigenesis and development of esophageal squamous cell carcinoma via activating the MEK/ERK/p90RSK signaling pathway.
Nan, et al.
Carcinogenesis, 41, 1263-1272 (2020)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| N8141-1G | 04061835559572 |
| N8141-250MG | 04061835559589 |
| N8141-5G | 04061835559596 |