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Merck
CN

W355690

肉豆蔻酸异丙酯

≥98%

别名:

十四碳酸异丙酯, 十四酸异丙酯

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关于此项目

线性分子式:
CH3(CH2)12COOCH(CH3)2
化学文摘社编号:
分子量:
270.45
FEMA Number:
3556
Council of Europe no.:
386
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.105
EC Number:
203-751-4
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
1781127
eCl@ss:
39022421
Organoleptic:
faint; fatty; oily
Grade:
Fragrance grade, Halal, Kosher
Biological source:
synthetic
Agency:
follows IFRA guidelines
Food allergen:
no known allergens
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biological source

synthetic

Quality Level

grade

Fragrance grade, Halal, Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009

assay

≥98%

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

faint; fatty; oily

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

General description

肉豆蔻酸异丙酯主要用作化妆品和外用药物的增溶剂、乳化剂和润肤剂。它还被用作食品工业中的调味剂。

Application


  • 负载富含黄酮类化合物的姜属植物纳米结构脂质载体的开发:本研究开发了用于从姜黄中提取的黄酮类化合物的纳米结构脂质载体,利用肉豆蔻酸异丙酯稳定这些载体并改善生物活性化合物的递送。(Shazwani SS 等人,2024 年

  • 利格列汀经皮递送物理和化学增强技术的比较评估:该研究比较了多种用于经皮药物递送的增强方法,包括使用异丙基肉豆蔻酸酯,突出了其在渗透增强技术中的有效性。(Karve T 等人,2024 年)

  • 利用响应面法优化花椒酰胺脂质体条件及其在 Caco-2 细胞单层模型中的吸收特性:本研究优化了含有花椒酰胺的脂质体配方,其中肉豆蔻酸异丙酯在脂质体稳定性和吸收特性中至关重要。(Wang R 等人,2024 年)

Biochem/physiol Actions

1.0% 时的气味
10ppm 时的味道

Disclaimer

仅供R&D或非EU食品使用不用于零售。


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存储类别

10 - Combustible liquids

wgk

awg

flash_point_f

>302.0 °F

flash_point_c

> 150 °C

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Handbook of Preservatives, 425-425 (2004)
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and



全球贸易项目编号

货号GTIN
W355690-20KG-K04061837530296
W355690-SAMPLE-K04061837536786
W355690-1KG-K04061837536779
W355690-8KG-K04061835567140