产品名称
菜油甾醇, Avanti Research™ - A Croda Brand 700126P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700126P-1mg), pkg of 1 × 10 mg (700126P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700126P
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC1CCC2(C3C(C4C(C(CC4)C(CCC(C(C)C)C)C)(CC3)C)CC=C2C1)C
InChI
1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3
InChI key
SGNBVLSWZMBQTH-UHFFFAOYSA-N
General description
菜油甾醇是一种植物甾醇，是胆固醇的类似物和油菜素甾醇（BR）的前体。diminute/dwarf1酶介导了从24-亚甲基胆固醇进行菜油甾醇的合成。菜油甾醇在胆固醇侧链的C-24位上具有甲基基团。
Application
菜油甾醇可作为一种植物甾醇用于检测其对乳腺癌细胞中肝脏X受体α（LXRA）转录激活的影响。它可在液相色谱多反应监测（LC-MRM）分析中作为甾醇标准品用于生成校准曲线。
Biochem/physiol Actions
菜油甾醇可降低乳糜微粒、低密度脂蛋白（LDL）和极低密度脂蛋白（VLDL）-apoB100的水平。高比例的菜油甾醇/谷甾醇可提高棉纤维的纤维伸长率。
Packaging
5 mL琥珀色玻璃螺旋盖小瓶（700126P-10mg）
5 mL琥珀色玻璃螺旋盖小瓶（700126P-1mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Samantha A Hutchinson et al.
International journal of molecular sciences, 20(13) (2019-07-05)
Low fruit and vegetable consumption and high saturated fat consumption causes elevated circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, oxysterols form that bind and activate the liver X receptors (LXRs). Oxysterols halt breast cancer cell proliferation
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 700126P-10MG | 04061835383863 |
| 700126P-1MG | 04061835383870 |