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Merck
CN

810154P

Avanti

16:0-12:0 NBD PE

Avanti Research - A Croda Brand

别名:

1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine

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关于此项目

经验公式(希尔记法):
C39H68N5O11P
化学文摘社编号:
分子量:
813.96
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

16:0-12:0 NBD PE, Avanti Research - A Croda Brand 810154P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810154P-1mg), pkg of 5 × 1 mg (810154P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810154P

shipped in

dry ice

storage temp.

−20°C

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe localized at the membrane interface. It possess fluorescent NBD label attached to the headgroup of phosphatidylethanolamine (PE). PE is the parent compound for phosphatidylcholine and phosphatidylethanolamine synthesis and is mostly enriched in brain.

Application

16:0-12:0 NBD PE has been used in lipid extraction assay and in vitro phospholipid fluorescence resonance energy transfer (FRET) assays. It is suitable for the determination of enzyme substrate specificity of lipoteichoic acid synthase (LtaS).

Biochem/physiol Actions

Phosphoethanolamine (PE) plays a vital role in the prevention of tumor proliferation. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) monitors the Red edge excitation shift (REES) phenomenon with the unique motional and dielectric properties it possesses.

Packaging

5 mL Amber Glass Screw Cap Vial (810154P-1mg)
5 mL Amber Glass Screw Cap Vial (810154P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids



历史批次信息供参考:

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Theoretical Study of Phosphoethanolamine: A Synthetic Anticancer Agent with Broad Antitumor Activity
Lorenzo VP, et al.
Journal of Chemistry, 2016 (2016)
Ouma Onguka et al.
The Journal of biological chemistry, 290(20), 12744-12752 (2015-04-02)
Phosphatidylethanolamine (PE) is a major cellular phospholipid that can be made by four separate pathways, one of which resides in the mitochondrion. The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p). The pool of PE produced by Psd1p



全球贸易项目编号

货号GTIN
810154P-1MG04061835185467
810154P-5MG04061835185474