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关于此项目
经验公式（希尔记法）:
C50H92BF2N6O20P3
化学文摘社编号:
分子量:
1239.02
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
TopFluor™ PI(3,5)P2, Avanti Research™ - A Croda Brand 810186P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 50 μg (with stopper and crimp cap (810186P-50ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 810186P
shipped in
dry ice
storage temp.
−20°C
General description
PI(3,5)P2 (1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-3,5-bisphosphate) is an endosomal lipid. It is produced by Fab1 phosphatidylinositol-3-phosphate 5-kinase from phosphatidylinositol 3-phosphate. This synthesis occurs in the lysosomal membranes.
Biochem/physiol Actions
Phosphatidylinositol phosphate lipids are associated with serval cell signalling pathways. It participates in the transport of peripheral membrane proteins along the plasma membrane. PI(3,5)P2 is essential for endosome maturation.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (810186P-50ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Interactions and Translational Dynamics of Phosphatidylinositol Bisphosphate (PIP2) Lipids in Asymmetric Lipid Bilayers.
Shi X, et al.
Testing, 32(41), 1732-1741 (2016)
The phosphatidylinositol 3, 5-bisphosphate (PI (3, 5) P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis
Han BK and Emr SD
The Journal of Biological Chemistry, 288(28), 20633-20645 (2013)
The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection
Nelson EA, et al.
PLoS Neglected Tropical Diseases, 11(4), e0005540-e0005540 (2017)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 810186P-500UG | 04065272070430 |
| 810186P-250UG | 04065272070423 |
| 810186P-50UG | 04061835190133 |