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Merck
CN

810225P

Avanti

18:1 Dansyl PS

Avanti Research - A Croda Brand

别名:

1,2-dioleoyl-sn-glycero-3-phospho-L-serine-N-(5-dimethylamino-1-naphthalenesulfonyl) (ammonium salt)

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关于此项目

经验公式(希尔记法):
C54H95N4O12PS
化学文摘社编号:
分子量:
1055.39
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810225P-1mg), pkg of 5 × 1 mg (810225P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

fluorescent lipids

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylserine (PS) belongs to the class of glycerophospholipids and is generally found in the inner leaflet of the plasma membrane and in endocytic membranes. Dansyl ((dimethyl amino)naphthalene-1-sulfonYL)) group produces blue or blue-green fluorescent adduct and is used in labeling techniques for studying protein folding and dynamics.(5)

Application

18:1 Dansyl PS may be used for preparation of liposomes for sedimentation assays, visualising and other fluorometric analysis like FRET.

Biochem/physiol Actions

Phosphatidylserine (PS) plays a vital role in cell cycle signaling and engulfing apoptotic cells. It is also known to activate the blood coagulation process acting as a pro-coagulant surface.

Packaging

5 mL Amber Glass Screw Cap Vial (810225P-1mg)
5 mL Amber Glass Screw Cap Vial (810225P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Laurent Meertens et al.
Cell host & microbe, 12(4), 544-557 (2012-10-23)
Dengue viruses (DVs) are responsible for the most medically relevant arboviral diseases. However, the molecular interactions mediating DV entry are poorly understood. We determined that TIM and TAM proteins, two receptor families that mediate the phosphatidylserine (PtdSer)-dependent phagocytic removal of
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly



全球贸易项目编号

货号GTIN
810225P-5MG04061835185580
810225P-1MG04061835185573