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Merck
CN

810283P

Avanti

TopFluor PS

Avanti Research - A Croda Brand

别名:

1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phospho-L-serine (ammonium salt)

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关于此项目

经验公式(希尔记法):
C46H80BF2N4O10P
化学文摘社编号:
分子量:
928.93
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

TopFluor PS, Avanti Research - A Croda Brand 810283P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810283P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810283P

shipped in

dry ice

storage temp.

−20°C

General description

TopFluor, a fluorescent molecule carries dipyrromethene boron difluoride moiety. It is linked to several lipid molecules by means of covalent attachment. Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Application

TopFluor PS may be used in liposome generation and as a synthetic fluorescent phosphoserine (PS) analogue to study PS distribution and dynamics in mouse embryonic fibroblasts (MEFs). It has also been used in the preparation of donor liposomes.

Biochem/physiol Actions

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. PS actively participates in the locomotor functions, like rapid reactions and reflexes.

Packaging

5 mL Amber Glass Screw Cap Vial (810283P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies
Conrad KS, et al.
Nature Communications, 8(1908), 1-13 (2017)
Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease
Hernandez-Alvarez MI, et al.
Cell, 177(4), 881-895 (2019)
Phosphatidylserine dynamics in cellular membranes
Kay JG, et al.
Molecular Biology of the Cell, 23(11), 2198-2212 (2012)



全球贸易项目编号

货号GTIN
810283P-1MG04061835190560