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Merck
CN

850368C

Avanti

20:0 PC

Avanti Research - A Croda Brand

别名:

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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关于此项目

经验公式(希尔记法):
C48H96NO8P
化学文摘社编号:
分子量:
846.25
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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产品名称

20:0 PC, 1,2-diarachidoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850368C-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850368C

concentration

10 mg/mL (850368C-25mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

InChI key

YKIOPDIXYAUOFN-YACUFSJGSA-N

General description

The mucosal layer of the colon has phosphatidylcholine (PC) as a vital constituent.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

20:0 PC has been used in collision cross section (CCS) calibration mixture for lipid identification.
It may be used:
  • as a component in giant unilamellar vesicles (GUVs) for a two-photon fluorescence microscopy study
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization
  • as a component in giant unilamellar vesicles (GUVs) to study its interaction with Crotalus atrox-secreted phospholipase A2 (sPLA2)

Biochem/physiol Actions

Phosphatidylcholine (PC) may participate in the signaling of neuronal differentiation. It can serve as a surfactant to block the penetrance of bacteria by generating a hydrophobic surface.

Packaging

5 mL Clear Glass Sealed Ampule (850368C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

危险化学品
易制毒化学品(2类)

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The Use of LipidIMMS Analyzer for Lipid Identification in Ion Mobility-Mass Spectrometry-Based Untargeted Lipidomics
Ion Mobility-Mass Spectrometry, 269-282 (2020)
Susana A Sanchez et al.
Biophysical journal, 82(4), 2232-2243 (2002-03-28)
We describe the interaction of Crotalus atrox-secreted phospholipase A2 (sPLA2) with giant unilamellar vesicles (GUVs) composed of single and binary phospholipid mixtures visualized through two-photon excitation fluorescent microscopy. The GUV lipid compositions that we examined included 1-palmitoyl-2-oleoyl-phosphatidylcholine, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and
Luciana Paoletti et al.
IUBMB life, 63(9), 714-720 (2011-08-06)
Neuronal differentiation is characterized by neuritogenesis and neurite outgrowth, processes, which are critically dependent on membrane biosynthesis, and therefore, on the expression and regulation of enzymes involved in phospholipid biosynthesis. During the last decade a great effort was made to



全球贸易项目编号

货号GTIN
850368C-25MG04061837792274