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关于此项目
经验公式（希尔记法）:
C40H80NO8P
化学文摘社编号:
分子量:
734.04
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
产品名称
14:0-18:0 PC, 1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (850446P-200mg), pkg of 1 × 25 mg (850446P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 850446P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
InChI
1S/C40H80NO8P/c1-6-8-10-12-14-16-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41(3,4)5)36-46-39(42)32-30-28-26-24-22-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
InChI key
TYAQXZHDAGZOEO-KXQOOQHDSA-N
General description
磷脂酰胆碱（PC）是结肠′粘膜层最重要的成分之一。14:0-18:0 PC（1-肉豆蔻酰基-2-硬脂酰基-sn-甘油-3-磷酸胆碱）是具有长烷基侧链的不对称脂质。
Application
14:0-18:0 PC（1-肉豆蔻酰基-2-硬脂酰基-sn-甘油-3-磷酸胆碱）可用于：
- 脂质双层，采用差示扫描量热法（DSC）研究其与d-赤型-N-棕榈酰基-鞘磷脂（16:0-SM）的混溶性，
- 作为脂质体中的不对称脂质成分，研究双层面积和脂质几何形状的影响，并作为脂质体增溶剂
- 制备用于溶栓研究的低温敏感脂质体
Biochem/physiol Actions
磷脂酰胆碱（PC）通过充当表面活性剂在粘液中形成疏水表面，从而抑制细菌的渗透。
Packaging
5 mL棕色玻璃螺旋盖小瓶（850446P-200mg）
5 mL棕色玻璃螺旋盖小瓶（850446P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
Joshua Owen et al.
Journal of controlled release : official journal of the Controlled Release Society, 319, 222-233 (2020-01-01)
The purpose of this exploratory study was to investigate the combination of a radiopharmaceutical, nanoparticles and ultrasound (US) enhanced delivery to develop a clinically viable therapeutic strategy for tumours overexpressing the epidermal growth factor receptor (EGFR). Molecularly targeted radionuclides have
Van Du Nguyen et al.
ACS applied materials & interfaces, 12(9), 10130-10141 (2020-02-12)
Although great efforts have been undertaken to develop a nanoparticle-based drug delivery system (DDS) for the treatment of solid tumors, the therapeutic outcomes are still limited. Immune cells, which possess an intrinsic ability to phagocytose nanoparticles and are recruited by
Bohdana Térová et al.
Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)
In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 850446P-200MG | 04061835230808 |
| 850446P-25MG | 04061835230815 |