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855475P

Avanti

12:0 Lyso PC

Avanti Research™ - A Croda Brand

别名:

1-十二烷酰基-sn-甘油-3-磷酸胆碱；PC(12:0/0:0)

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关于此项目

经验公式（希尔记法）:
C20H42NO7P
化学文摘社编号:
20559-18-6
分子量:
439.52
MDL number:
MFCD00133434
UNSPSC Code:
51191904
NACRES:
NA.25
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产品名称

12:0 Lyso PC, Avanti Research™ - A Croda Brand

description

1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine

assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 200 mg (855475P-200mg), pkg of 1 × 25 mg (855475P-25mg), pkg of 1 × 500 mg (855475P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCC)=O

InChI

1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1

InChI key

BWKILASWCLJPBO-LJQANCHMSA-N

General description

溶血磷脂酰胆碱（LPC）是一种在病理反应中分泌的具有生物活性的促炎脂质。它在其极性头部有一个胆碱基团。溶血磷脂酰胆碱（Lyso-PC）是血浆、血管组织和脂蛋白的成分。

Application

12:0 Lyso PC已用于研究其神经形成活性和外源性脂质的应用。

Biochem/physiol Actions

溶血磷脂酰胆碱（LPC）改变不同细胞类型的各种功能，例如内皮细胞，平滑肌细胞，单核细胞，巨噬细胞和T细胞。它与动脉硬化症和炎症性疾病有关。LPC激活许多第二信使，包括蛋白激酶C、细胞外信号调节激酶和蛋白酪氨酸激酶。

Packaging

20 mL透明玻璃螺旋盖小瓶（855475P-500mg）
5 mL棕色玻璃螺旋盖小瓶（855475P-200mg）
5 mL棕色玻璃螺旋盖小瓶（855475P-25mg）

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor
Ikeno Y, et al.
Test, 280(30) (2005)
Inner/outer nuclear membrane fusion in nuclear pore assembly: biochemical demonstration and molecular analysis
Fichtman B, et al.
Molecular Biology of the Cell, 21(23) (2010)
Boris Fichtman et al.
Molecular biology of the cell, 21(23), 4197-4211 (2010-10-12)
Nuclear pore complexes (NPCs) are large proteinaceous channels embedded in double nuclear membranes, which carry out nucleocytoplasmic exchange. The mechanism of nuclear pore assembly involves a unique challenge, as it requires creation of a long-lived membrane-lined channel connecting the inner
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全球贸易项目编号

货号GTIN
855475P-25MG04061835231522
855475P-200MG04061835231515
855475P-500MG04061835231539