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关于此项目
经验公式（希尔记法）:
C28H55NO3
化学文摘社编号:
分子量:
453.74
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C10 Ceramide (d18:1/10:0), Avanti Research™ - A Croda Brand 860510P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860510P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860510P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1
InChI key
FDWVAQFAMZLCAX-NBNLIBPQSA-N
General description
C10 Ceramide (d18:1/10:0) is a synthetic ceramide containing sphingosine with decanoic acid. It has a short acyl chain length than sphingosine acyl chain.
Application
C10 Ceramide (d18:1/10:0) or N-decanoyl-D-erythro-sphingosine has been used:
- as an internal standard in galactocerebrosidase (GALC) assay
- to study its role on the physical properties of edible organogels and on their ability to induce cell death of various cancer cell lines
- to study its mixing behavior with other ceramides having the same sphingosine base but varying N-linked acyl chain length
Biochem/physiol Actions
Ceramides modulate stress responses and inflammation. It also controls cell differentiation, proliferation and apoptosis.
Packaging
5 mL Amber Glass Screw Cap Vial (860510P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Meenu N Perera et al.
Chemistry and physics of lipids, 194, 110-116 (2015-09-27)
A ceramide commonly found in mammalian cells, C16-ceramide (N-palmitoyl-d-erythro-sphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C16-ceramide is unable to permeabilize the plasma membrane of erythrocytes. This specificity is unexpected considering that ceramide
Zhixing Wang et al.
The Journal of investigative dermatology, 133(3), 668-676 (2012-10-26)
The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860510P-5MG | 04061835317493 |