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关于此项目
经验公式（希尔记法）:
C48H91NO8
化学文摘社编号:
分子量:
810.24
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C24:1 Galactosyl(β) Ceramide (d18:1/24:1(15Z)), Avanti Research™ - A Croda Brand 860546P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860546P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860546P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O
InChI
1S/C48H91NO8/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-44(52)49-41(40-56-48-47(55)46(54)45(53)43(39-50)57-48)42(51)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,41-43,45-48,50-51,53-55H,3-16,19-34,36,38-40H2,1-2H3,(H,49,52)/b18-17-,37-35+/t41?,42-,43-,45+,46+,47-,48+/m1/s1
InChI key
WBOZIXHPUPAOIA-KVGFKTOYSA-N
General description
β-Galactosylceramides (GalCers) or cerebrosides are synthesized from the glycosphingolipids by or β-GalCer synthase. They are localized in cytosolic face cell membrane after synthesis from Golgi and endoplasmic reticulum. GalCers are present in the brain and myelin structures.
Application
C24:1 Galactosyl(β) Ceramide (d18:1/24:1(15Z)) is suitable for use
- as a standard hexosylceramide for hydrophilic interaction chromatography-based liquid chromatography mass spectroscopy
- as a lipid standard in ozone-induced dissociation mass spectrometry
- in lipid nanotubes (LNT) preparation in combination with phosphatidylserine
Biochem/physiol Actions
β-Galactosylceramides (GalCers) levels are elevated in Krabbe′s disease due to the galactosylceramidase enzyme deficiency. High levels of nervonic acid-containing ceramide (d18:1/24:1) is associated with aging.
Packaging
5 mL Amber Glass Screw Cap Vial (860546P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus
Vozella V, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862(12), 1502-1511 (2017)
Characterization and direct quantitation of cerebroside molecular species from lipid extracts by shotgun lipidomics
Han X and Cheng H
Journal of Lipid Research, 46(1), 163-175 (2005)
Helical organization of blood coagulation factor VIII on lipid nanotubes
Miller J, et al.
Journal of Visualized Experiments, 28(88), e51254-e51254 (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860546P-5MG | 04061835318056 |