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Merck
CN

860573P

Avanti

C12 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/12:0)

Avanti Research - A Croda Brand

别名:

3-O-sulfo-D-galactosyl-β1-1′-N-lauroyl-D-erythro-sphingosine (ammonium salt), (synthetic)

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关于此项目

经验公式(希尔记法):
C36H72N2O11S
化学文摘社编号:
分子量:
741.03
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

C12 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/12:0), Avanti Research - A Croda Brand 860573P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860573P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860573P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]

InChI

1S/C36H69NO11S.H3N/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-30(39)29(37-32(40)26-24-22-20-17-12-10-8-6-4-2)28-46-36-34(42)35(48-49(43,44)45)33(41)31(27-38)47-36;/h23,25,29-31,33-36,38-39,41-42H,3-22,24,26-28H2,1-2H3,(H,37,40)(H,43,44,45);1H3/b25-23+;/t29-,30+,31?,33-,34?,35?,36+;/m0./s1

InChI key

ZRHCDEVQWSMWDC-LNTPIPJUSA-N

Application

C12 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/12:0) is suitable for use as a standard in mass spectrometric analysis of sulfatides.

Biochem/physiol Actions

C12 Mono-Sulfo Galactosyl(β) Ceramide (d18:1/12:0) is a non-physical sulfatide. Accumulation of sulfatide impairs the activity of arylsulfatase A enzyme, which in turn leads to the development of genetic disease, metachromatic leukodystrophy.

Packaging

5 mL Amber Glass Screw Cap Vial (860573P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


存储类别

11 - Combustible Solids

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

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Quantification of plasma sulfatides by mass spectrometry: Utility for metachromatic leukodystrophy
Saville J, et al.
Analytica Chimica Acta, 955, 79-85 (2017)
Michela Antonelli et al.
Analytical and bioanalytical chemistry, 412(2), 413-423 (2019-11-25)
The chemical composition of Cannabis sativa L. has been extensively investigated for several years; nevertheless, a detailed lipidome characterization is completely lacking in the literature. To achieve this goal, an extraction and enrichment procedure was developed for the characterization of
Mariachiara Bianco et al.
Food chemistry, 324, 126878-126878 (2020-04-29)
Ceramides (Cer) and cerebrosides are important sphingolipids (SL) involved in many biological processes. Herein, the SL content of yellow lupin seeds (Lupinus luteus) was determined by liquid-liquid extraction, mild alkaline hydrolysis (1 h at 37 °C) and reversed-phase liquid chromatography with negative



全球贸易项目编号

货号GTIN
860573P-1MG04061835318179