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Merck
CN

860632P

Avanti

C14 dihydroceramide (d18:0/14:0)

Avanti Research - A Croda Brand

别名:

N-myristoyl-D-erythro-sphinganine

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关于此项目

经验公式(希尔记法):
C32H65NO3
化学文摘社编号:
分子量:
511.86
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

C14 dihydroceramide (d18:0/14:0), Avanti Research - A Croda Brand 860632P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (860632P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860632P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC

InChI

1S/C32H65NO3/c1-3-5-7-9-11-13-15-16-18-19-21-23-25-27-31(35)30(29-34)33-32(36)28-26-24-22-20-17-14-12-10-8-6-4-2/h30-31,34-35H,3-29H2,1-2H3,(H,33,36)/t30-,31+/m0/s1

InChI key

UDTSZXVRDXQARY-IOWSJCHKSA-N

General description

C14 dihydroceramide is a synthetic dihydroceramide. Acylation of sphinganine with myristoyl (FA-CoA with C14 acyl chain) by dihydro ceramide synthase 1, yields C14-dihydroceramide.

Application

C14 dihydroceramide has been used as a standard for measuring the concentration of sphingolipid metabolites in adipose tissues by quadrupole time-of-flight (Q-TOF) mass spectrometry.

Packaging

5 mL Amber Glass Screw Cap Vial (860632P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Erwan Beauchamp et al.
Biochimie, 89(12), 1553-1561 (2007-08-25)
Dihydroceramide Delta4-desaturase (DES) catalyzes the desaturation of dihydroceramide into ceramide. In mammals, two gene isoforms named DES1 and DES2 have recently been identified. The regulation of these enzymes is still poorly understood. This study was designed to examine the possible
Sabine Grösch et al.
Progress in lipid research, 51(1), 50-62 (2011-12-03)
Ceramides are a class of sphingolipids that are abundant in cell membranes. They are important structural components of the membrane but can also act as second messengers in various signaling pathways. Until recently, ceramides and dihydroceramides were considered as a
Thomas D Mullen et al.
Journal of lipid research, 52(1), 68-77 (2010-10-14)
Mammalian ceramide synthases 1 to 6 (CerS1-6) generate Cer in an acyl-CoA-dependent manner, and expression of individual CerS has been shown to enhance the synthesis of ceramides with particular acyl chain lengths. However, the contribution of each CerS to steady-state



全球贸易项目编号

货号GTIN
860632P-5MG04061835318780