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关于此项目
经验公式（希尔记法）:
C42H76D7NO3
化学文摘社编号:
分子量:
657.16
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352100
Assay:
>99% (TLC)
Form:
powder
产品名称
C24 神经酰胺-d7 (d18:1-d7/24:0), Avanti Research™ - A Croda Brand 860678P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860678P-1mg), pkg of 1 × 5 mg (860678P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860678P
shipped in
dry ice
storage temp.
−20°C
General description
C24神经酰胺（d18:1/24:0）是一种含有鞘氨醇和木质酸的合成神经酰胺。 神经酰胺合成酶2负责C24 神经酰胺的合成。C24神经酰胺（d18:1-d7/24:0）是C24 神经酰胺（d18:1/24:0）的氘代衍生物 。
Application
C24神经酰胺d7（d18:1-d7/24:0）已被用作液相色谱-质谱联用（LC-MS）法定量分析骨骼肌中C24 神经酰胺的标准品。
Biochem/physiol Actions
C24神经酰胺在诱导细胞死亡中起着至关重要的作用。在肿瘤监控中C24神经酰胺水平的变化可能是一个潜在的指标。测定人血浆中神经酰胺 (Cer) d18:1/16:0、Cer d18:1/18:0、Cer d18:1/24:0和Cer d18:1/24:1的水平和比例有助于预测冠状动脉疾病的致命结果。C24神经酰胺 (d18:1/24:0) 的稳定同位素形式可方便地用于经过验证的新液相色谱-串联字谱联用方法进行临床规模的测量。
Packaging
5 mL 琥珀色玻璃螺旋盖小瓶 (860678P-1 mg)
5 mL 琥珀色玻璃螺旋盖小瓶 (860678P-5 mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860678P-1MG | 04061835186686 |