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关于此项目
经验公式（希尔记法）:
C42H74D7NO3
化学文摘社编号:
分子量:
655.14
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
产品名称
C24:1 神经酰胺-d7 (d18:1-d7/24:1 (15Z)), Avanti Research™ - A Croda Brand 860679P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860679P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860679P
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
InChI key
VJSBNBBOSZJDKB-PVDQZAGSSA-N
General description
C24:1 神经酰胺（d18:1/24:1）是来源于鞘氨醇与神经酸（木蜡酸（24：0）的单不饱和类似物）的合成神经酰胺。C24:1 神经酰胺-d7(d18:1-d7/24:1(15Z)) 是C24:1神经酰胺的氘代衍生物 (d18:1/24:1).。
Application
C24:1 神经酰胺-d7 (d18:1-d7/24:1(15Z)) 已被用作液相色谱-质谱法（LC-MS）定量测定骨骼肌中C24:1神经酰胺的标准品。它还被用作通过thermo Q-Exactive四极杆-静电场轨道阱质谱（quadrupole-orbitrap mass spectrometery）测量斑马鱼大脑和人胚胎肾细胞系（HEK293）中C40-C44神经酰胺的标准品。
Biochem/physiol Actions
监测人血浆中神经酰胺 (Cer) d18:1/16:0、Cer d18:1/18:0、Cer d18:1/24:0和 Cer d18:1/24:1 的水平及其比率有助于冠状动脉疾病致命结果的预后。稳定同位素形式的C24:1神经酰胺（d18:1/24:1）适用于研究人员新近描述的经过验证的液相色谱-串联质谱方法，用于其临床规模的测量。
Packaging
5 mL 棕色玻璃螺旋盖小瓶 (860679P-1 mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
flash_point_f
No data available
flash_point_c
No data available
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery
Tejia Zhang et al.
Scientific reports, 9(1), 19939-19939 (2019-12-29)
Extensive characterisations of the zebrafish genome and proteome have established a foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafish lipidome has not been as comprehensive. In an effort to expand current knowledge
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 860679P-1MG | 04061835191840 |