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Merck
CN

870716P

Avanti

16:0辅酶A

Avanti Research - A Croda Brand

别名:

棕榈酰辅酶A铵盐

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关于此项目

经验公式(希尔记法):
C37H75N10O17P3S
化学文摘社编号:
分子量:
1057.03
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

16:0辅酶A, Avanti Research - A Croda Brand 870716P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (870716P-10mg), pkg of 1 × 25 mg (870716P-25mg), pkg of 1 × 5 mg (870716P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 870716P

application(s)

lipidomics

lipid type

coenzymes

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@@](C(NCCC(NCCSC(CCCCCCCCCCCCCCC)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]1OP([O-])(O)=O)O[C@H]([C@@H]1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]

InChI

1S/C37H66N7O17P3S.3H3N/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44;;;/h24-26,30-32,36,47-48H,4-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52);3*1H3/t26-,30?,31+,32+,36-;;;/m1.../s1

InChI key

VJXJWGKNGIGUQX-AUCFWDBISA-N

General description

16:0辅酶A,又称为棕榈酰辅酶A,是含量最为丰富的酰基-CoA,是β-氧化的第一轮产物。它可作为反应底物,在蛋白酰基转移酶催化下通过棕榈酰化反应将棕榈酰基转移到靶标蛋白的游离巯基上。

Application

16:0辅酶A已用作:
  • 分枝杆菌细胞内棕榈酰-CoA质谱法定量分析的标准品
  • 蛋白体外结合实验的结合缓冲液组分
  • 丝氨酸棕榈酰基转移酶的测定底物

Packaging

5 mL棕色玻璃螺旋盖小瓶 (870716P-10mg)
5 mL棕色玻璃螺旋盖小瓶 (870716P-25mg)
5 mL棕色玻璃螺旋盖小瓶 (870716P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cheryl Budde et al.
Methods (San Diego, Calif.), 40(2), 143-150 (2006-10-03)
Palmitoylation enhances membrane association and plays a role in the subcellular trafficking and signaling function of proteins. Unlike other forms of protein lipidation, such as prenylation and myristoylation, palmitoylation is reversible and can therefore play a regulatory role. Enzyme activities
Oshrit Ben-David et al.
The Journal of biological chemistry, 286(34), 30022-30033 (2011-06-28)
Sphingolipids (SLs) act as signaling molecules and as structural components in both neuronal cells and myelin. We now characterize the biochemical, histological, and behavioral abnormalities in the brain of a mouse lacking very long acyl (C22-C24) chain SLs. This mouse
Anke Penno et al.
The Journal of biological chemistry, 285(15), 11178-11187 (2010-01-26)
HSAN1 is an inherited neuropathy found to be associated with several missense mutations in the SPTLC1 subunit of serine palmitoyltransferase (SPT). SPT catalyzes the condensation of serine and palmitoyl-CoA, the initial step in the de novo synthesis of sphingolipids. Here



全球贸易项目编号

货号GTIN
870716P-10MG04061835187140
870716P-25MG04061835187157
870716P-5MG04061835187164