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Merck
CN

878112P

Avanti

C16-18:1 PC

Avanti Research - A Croda Brand

别名:

1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine

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关于此项目

经验公式(希尔记法):
C42H84NO7P
化学文摘社编号:
分子量:
746.09
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

C16-18:1 PC, Avanti Research - A Croda Brand 878112P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (878112P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 878112P

lipid type

bioactive lipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COCCCCCCCCCCCCCCCC)=O

InChI key

SIEDNCDNGMIKST-IYEJTHTFSA-N

General description

C16-18:1 PC, also called as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of platelet-activating factor (PAF) family of glycerophospholipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.

Application

C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used in the liposome binding assay. It may also be used as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS).

Biochem/physiol Actions

Platelet-activating factor (PAF), a lipid mediator acts as a pro-inflammatory agent that exhibits variety of biological and pharmacological effects.

Packaging

5 mL Clear Glass Sealed Ampule (878112P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform
John J H Shin et al.
Developmental cell, 52(4), 461-476 (2020-01-14)
Phosphoinositides, diacylglycerolpyrophosphate, ceramide-1-phosphate, and phosphatidic acid belong to a unique class of membrane signaling lipids that contain phosphomonoesters in their headgroups having pKa values in the physiological range. The phosphomonoester headgroup of phosphatidic acid enables this lipid to act as



全球贸易项目编号

货号GTIN
878112P-5MG04061835353859