assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g, pkg of 1 × 5 g
manufacturer/tradename
Avanti Research™ - A Croda Brand
application(s)
advanced drug delivery
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=C(CCCCCCCCCCCCC)OCC(OC(CCCCCCCCCCCCC)=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
InChI key
NLDCRRFPGOSAHV-UHFFFAOYSA-N
General description
二肉豆蔻基甘油（DMG）分子可与类似于磷脂的膜缔合。
结构、分子式和分子量表示的是材料中平均聚合物长度。
Application
DMG-PEG 2000适用于制备用于microRNA 和短干扰RNA 递送的脂质纳米颗粒。
Biochem/physiol Actions
二肉豆蔻基甘油（DMG） − 聚乙二醇（PEG）2000被用于制备脂质体，从而用于肝细胞、胃肠道、神经内分泌和肾上腺皮质癌的抗癌药物递送研究。它也被用于制备siRNA（小干扰RNA）的脂质纳米颗粒。
Packaging
20 mL透明玻璃螺旋盖小瓶（880151P-1G）
60 mL棕色广口螺帽玻璃瓶(880151P-5G)
60 mL棕色广口螺帽玻璃瓶(880151P-5G)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Liver-Specific silencing of Lipin1 reduces fat mass as well as hepatic triglyceride biosynthesis in mice
Kajimoto K, et al.
Biological & Pharmaceutical Bulletin, 39(10), 1653-1661 (2016)
Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia
Huang X, et al.
Clinical Cancer Research, 19(9), 2355-2367 (2013)
Advances in lipid nanoparticles for siRNA delivery
Tam Y, et al.
Pharmaceutics, 5(3), 498-507 (2013)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 880151P-1G | 04061838814241 |
| 880151P-5G | 04061838814258 |